Gastric gastrointestinal stromal tumor smaller than 20 mm with liver metastasis

Akira Aso, Eikichi Ihara, Hiroaki Kubo, Takashi Osoegawa, takamasa ono, Kazuhiko Nakamura, Tetsuhide Ito, Yoshihiro Kakeji, Osada Mikako, Hidetaka Yamamoto, Tatsuhiro Oishi, Yayoi Oishi, Yoichi Hachitanda, Ryoichi Takayanagi

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Abstract

There have been no reports of gastric gastrointestinal stromal tumors (GISTs) <20 mm with distant metastasis. We report a case of a 15-mm gastric GIST with liver metastasis 1 year after surgical resection of the primary lesion. A 35-year-old man underwent routine esophagogastroduodenoscopy in July 2009. A submucosal tumor (SMT) <20 mm was incidentally detected at the posterior wall of the gastric body. Endoscopic ultrasound (EUS) indicated that it was a gastrointestinal mesenchymal tumor, including GIST, leiomyoma or schwannoma. He did not accept regular follow-up for this gastric SMT, therefore local laparoscopic excision was carried out in October 2009. The final pathological diagnosis after surgery was GIST, 15 mm in size, and a mitotic rate of 7/50 high-power fields, which did not indicate a high metastatic risk. The patient was followed up regularly without adjuvant chemotherapy. At 1 year after surgery, a space-occupying lesion ~15 mm was detected in the left lobe of the liver by abdominal ultrasound, where no mass lesion had been observed before surgery. To make a definite diagnosis of the hepatic mass lesion, EUS-guided fine-needle aspiration was performed, which demonstrated a metastatic liver tumor from a gastric GIST. Although this was a rare case, we should keep in mind that gastric GISTs do have a chance of malignant behavior, even if <20 mm.

Original languageEnglish
Pages (from-to)29-32
Number of pages4
JournalClinical Journal of Gastroenterology
Volume6
Issue number1
DOIs
Publication statusPublished - Feb 1 2013

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Gastrointestinal Stromal Tumors
Stomach
Neoplasm Metastasis
Liver
Neoplasms
Endoscopic Ultrasound-Guided Fine Needle Aspiration
Digestive System Endoscopy
Neurilemmoma
Leiomyoma
Adjuvant Chemotherapy

All Science Journal Classification (ASJC) codes

  • Gastroenterology

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Gastric gastrointestinal stromal tumor smaller than 20 mm with liver metastasis. / Aso, Akira; Ihara, Eikichi; Kubo, Hiroaki; Osoegawa, Takashi; ono, takamasa; Nakamura, Kazuhiko; Ito, Tetsuhide; Kakeji, Yoshihiro; Mikako, Osada; Yamamoto, Hidetaka; Oishi, Tatsuhiro; Oishi, Yayoi; Hachitanda, Yoichi; Takayanagi, Ryoichi.

In: Clinical Journal of Gastroenterology, Vol. 6, No. 1, 01.02.2013, p. 29-32.

Research output: Contribution to journalArticle

Aso, A, Ihara, E, Kubo, H, Osoegawa, T, ono, T, Nakamura, K, Ito, T, Kakeji, Y, Mikako, O, Yamamoto, H, Oishi, T, Oishi, Y, Hachitanda, Y & Takayanagi, R 2013, 'Gastric gastrointestinal stromal tumor smaller than 20 mm with liver metastasis', Clinical Journal of Gastroenterology, vol. 6, no. 1, pp. 29-32. https://doi.org/10.1007/s12328-012-0351-0
Aso, Akira ; Ihara, Eikichi ; Kubo, Hiroaki ; Osoegawa, Takashi ; ono, takamasa ; Nakamura, Kazuhiko ; Ito, Tetsuhide ; Kakeji, Yoshihiro ; Mikako, Osada ; Yamamoto, Hidetaka ; Oishi, Tatsuhiro ; Oishi, Yayoi ; Hachitanda, Yoichi ; Takayanagi, Ryoichi. / Gastric gastrointestinal stromal tumor smaller than 20 mm with liver metastasis. In: Clinical Journal of Gastroenterology. 2013 ; Vol. 6, No. 1. pp. 29-32.
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