Gastric phase 3 motility after pylorus-preserving p ancreatoduodenectomy

Ohtsuka Takao, Shunichi Takahata, Jiro Ohuchida, Torahiko Takeda, Hiroaki Matsunaga, Kazunori Yokohata, Koji Yamaguchi, Kazuo Chijiiwa, Masao Tanaka

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Objective: To analyze factors affecting the recovery course of phase 3 activity of the gastric migrating motor complex after pylorus-preserving pancreatoduodenectomy (PPPD) and investigate effects of the recovery of gastric phase 3 on gastric emptying after feeding. Summary Background Data: Whether early recovery of gastric phase 3 during fasting would predict early recovery of the fed-state gastric emptying function after PPPD has not been well documented. Methods: Manometric recording from the gastric antrum was repeated at a weekly interval until the first appearance of gastric phase 3 in 57 patients after PPPD. Twenty-three clinical parameters were assessed as possible factors affecting the recovery course of gastric phase 3 by simple and multiple regression analyses. A gastric emptying study after feeding of a test meal was performed by the acetaminophen method and the values were compared between patients with and without gastric phase 3 after PPPD. Results: The mean period before the first appearance of gastric phase 3 was 38 days. Among 23 parameters, only lymph node dissection along the hepatoduodenal ligament significantly delayed recovery of gastric phase 3 after PPPD by univariate and multivariate analyses. The presence or absence of gastric phase 3 in the early postoperative period did not influence gastric emptying after feeding in the intermediate period after PPPD. Conclusions: Avoiding lymph node dissection along the hepatoduodenal ligament, if applicable, may contribute to early recovery of gastric phase 3 after PPPD. The recovery state of gastric phase 3 during fasting, however, is not necessarily consistent with the degree of improvement of gastric emptying after feeding.

Original languageEnglish
Pages (from-to)417-423
Number of pages7
JournalAnnals of Surgery
Volume235
Issue number3
DOIs
Publication statusPublished - Mar 11 2002

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Pylorus
Stomach
Pancreaticoduodenectomy
Gastric Emptying
Lymph Node Excision
Ligaments
Fasting
Migrating Myoelectric Complexes
Pyloric Antrum
Acetaminophen
Postoperative Period
Statistical Factor Analysis
Meals
Multivariate Analysis
Regression Analysis

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

Takao, O., Takahata, S., Ohuchida, J., Takeda, T., Matsunaga, H., Yokohata, K., ... Tanaka, M. (2002). Gastric phase 3 motility after pylorus-preserving p ancreatoduodenectomy. Annals of Surgery, 235(3), 417-423. https://doi.org/10.1097/00000658-200203000-00014

Gastric phase 3 motility after pylorus-preserving p ancreatoduodenectomy. / Takao, Ohtsuka; Takahata, Shunichi; Ohuchida, Jiro; Takeda, Torahiko; Matsunaga, Hiroaki; Yokohata, Kazunori; Yamaguchi, Koji; Chijiiwa, Kazuo; Tanaka, Masao.

In: Annals of Surgery, Vol. 235, No. 3, 11.03.2002, p. 417-423.

Research output: Contribution to journalArticle

Takao, O, Takahata, S, Ohuchida, J, Takeda, T, Matsunaga, H, Yokohata, K, Yamaguchi, K, Chijiiwa, K & Tanaka, M 2002, 'Gastric phase 3 motility after pylorus-preserving p ancreatoduodenectomy', Annals of Surgery, vol. 235, no. 3, pp. 417-423. https://doi.org/10.1097/00000658-200203000-00014
Takao O, Takahata S, Ohuchida J, Takeda T, Matsunaga H, Yokohata K et al. Gastric phase 3 motility after pylorus-preserving p ancreatoduodenectomy. Annals of Surgery. 2002 Mar 11;235(3):417-423. https://doi.org/10.1097/00000658-200203000-00014
Takao, Ohtsuka ; Takahata, Shunichi ; Ohuchida, Jiro ; Takeda, Torahiko ; Matsunaga, Hiroaki ; Yokohata, Kazunori ; Yamaguchi, Koji ; Chijiiwa, Kazuo ; Tanaka, Masao. / Gastric phase 3 motility after pylorus-preserving p ancreatoduodenectomy. In: Annals of Surgery. 2002 ; Vol. 235, No. 3. pp. 417-423.
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