Gastric phase 3 motility after pylorus-preserving p ancreatoduodenectomy

Takao Ohtsuka, Shunichi Takahata, Jiro Ohuchida, Torahiko Takeda, Hiroaki Matsunaga, Kazunori Yokohata, Koji Yamaguchi, Kazuo Chijiiwa, Masao Tanaka

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Abstract

Objective: To analyze factors affecting the recovery course of phase 3 activity of the gastric migrating motor complex after pylorus-preserving pancreatoduodenectomy (PPPD) and investigate effects of the recovery of gastric phase 3 on gastric emptying after feeding. Summary Background Data: Whether early recovery of gastric phase 3 during fasting would predict early recovery of the fed-state gastric emptying function after PPPD has not been well documented. Methods: Manometric recording from the gastric antrum was repeated at a weekly interval until the first appearance of gastric phase 3 in 57 patients after PPPD. Twenty-three clinical parameters were assessed as possible factors affecting the recovery course of gastric phase 3 by simple and multiple regression analyses. A gastric emptying study after feeding of a test meal was performed by the acetaminophen method and the values were compared between patients with and without gastric phase 3 after PPPD. Results: The mean period before the first appearance of gastric phase 3 was 38 days. Among 23 parameters, only lymph node dissection along the hepatoduodenal ligament significantly delayed recovery of gastric phase 3 after PPPD by univariate and multivariate analyses. The presence or absence of gastric phase 3 in the early postoperative period did not influence gastric emptying after feeding in the intermediate period after PPPD. Conclusions: Avoiding lymph node dissection along the hepatoduodenal ligament, if applicable, may contribute to early recovery of gastric phase 3 after PPPD. The recovery state of gastric phase 3 during fasting, however, is not necessarily consistent with the degree of improvement of gastric emptying after feeding.

Original languageEnglish
Pages (from-to)417-423
Number of pages7
JournalAnnals of surgery
Volume235
Issue number3
DOIs
Publication statusPublished - Mar 11 2002

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All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

Ohtsuka, T., Takahata, S., Ohuchida, J., Takeda, T., Matsunaga, H., Yokohata, K., ... Tanaka, M. (2002). Gastric phase 3 motility after pylorus-preserving p ancreatoduodenectomy. Annals of surgery, 235(3), 417-423. https://doi.org/10.1097/00000658-200203000-00014