Gastrointestinal cancer and Herpes zoster in adults

Manabu Yamamoto, Hiroyuki Mine, Kohei Akazawa, Yoshihiko Maehara, Keizo Sugimachi

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background/Aims: Herpes zoster is associated with immunosuppression, and also has an increased risk of malignancy. The aim of this study is to determine whether patients with Herpes zoster are at a higher risk of occult malignancy and gastrointestinal diseases. Methodology: We examined 131 of 201 Japanese patients who showed evidence of Herpes zoster in the gastrointestinal tract including the large intestine using gastrointestinal endoscopy, total colonoscopy and CT scanning. Results: Six of 131 patients (4.6%) with Herpes zoster, who had undergone all three examinations, had malignancies. This rate is significantly higher than the predicted rate (P<0.05). Five of six patients had gastrointestinal or colon cancer. Previously, 17 of the 201 patients has been surgically treated for cancers (17/201=8.5%, predictable rate=8.9%), eleven of these 17 patients had surgery for gastric cancer, or for colon cancer etc. We also diagnosed three patients to have cancers after an episode of Herpes zoster, out of the 140 patients who we examined as study prospects (3/140=2.1%, relative risks=1.75). No significant increases in the malignant rates were observed before or after the onset of Herpes zoster. Conclusions: These findings are considered to support the policy to investigate patients with Herpes zoster for the presence of occult malignancies, though the rate of malignancy in such patients before or after episodes of Herpes zoster was not significantly different from that of the predictable rate.

Original languageEnglish
Pages (from-to)1043-1046
Number of pages4
JournalHepato-gastroenterology
Volume50
Issue number52
Publication statusPublished - Jul 1 2003

Fingerprint

Gastrointestinal Neoplasms
Herpes Zoster
Neoplasms
Colonic Neoplasms
Gastrointestinal Endoscopy
Gastrointestinal Diseases
Large Intestine
Colonoscopy
Immunosuppression
Stomach Neoplasms
Gastrointestinal Tract

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

Cite this

Yamamoto, M., Mine, H., Akazawa, K., Maehara, Y., & Sugimachi, K. (2003). Gastrointestinal cancer and Herpes zoster in adults. Hepato-gastroenterology, 50(52), 1043-1046.

Gastrointestinal cancer and Herpes zoster in adults. / Yamamoto, Manabu; Mine, Hiroyuki; Akazawa, Kohei; Maehara, Yoshihiko; Sugimachi, Keizo.

In: Hepato-gastroenterology, Vol. 50, No. 52, 01.07.2003, p. 1043-1046.

Research output: Contribution to journalArticle

Yamamoto, M, Mine, H, Akazawa, K, Maehara, Y & Sugimachi, K 2003, 'Gastrointestinal cancer and Herpes zoster in adults', Hepato-gastroenterology, vol. 50, no. 52, pp. 1043-1046.
Yamamoto M, Mine H, Akazawa K, Maehara Y, Sugimachi K. Gastrointestinal cancer and Herpes zoster in adults. Hepato-gastroenterology. 2003 Jul 1;50(52):1043-1046.
Yamamoto, Manabu ; Mine, Hiroyuki ; Akazawa, Kohei ; Maehara, Yoshihiko ; Sugimachi, Keizo. / Gastrointestinal cancer and Herpes zoster in adults. In: Hepato-gastroenterology. 2003 ; Vol. 50, No. 52. pp. 1043-1046.
@article{7662e96a6ab04829b14b58fca9aec128,
title = "Gastrointestinal cancer and Herpes zoster in adults",
abstract = "Background/Aims: Herpes zoster is associated with immunosuppression, and also has an increased risk of malignancy. The aim of this study is to determine whether patients with Herpes zoster are at a higher risk of occult malignancy and gastrointestinal diseases. Methodology: We examined 131 of 201 Japanese patients who showed evidence of Herpes zoster in the gastrointestinal tract including the large intestine using gastrointestinal endoscopy, total colonoscopy and CT scanning. Results: Six of 131 patients (4.6{\%}) with Herpes zoster, who had undergone all three examinations, had malignancies. This rate is significantly higher than the predicted rate (P<0.05). Five of six patients had gastrointestinal or colon cancer. Previously, 17 of the 201 patients has been surgically treated for cancers (17/201=8.5{\%}, predictable rate=8.9{\%}), eleven of these 17 patients had surgery for gastric cancer, or for colon cancer etc. We also diagnosed three patients to have cancers after an episode of Herpes zoster, out of the 140 patients who we examined as study prospects (3/140=2.1{\%}, relative risks=1.75). No significant increases in the malignant rates were observed before or after the onset of Herpes zoster. Conclusions: These findings are considered to support the policy to investigate patients with Herpes zoster for the presence of occult malignancies, though the rate of malignancy in such patients before or after episodes of Herpes zoster was not significantly different from that of the predictable rate.",
author = "Manabu Yamamoto and Hiroyuki Mine and Kohei Akazawa and Yoshihiko Maehara and Keizo Sugimachi",
year = "2003",
month = "7",
day = "1",
language = "English",
volume = "50",
pages = "1043--1046",
journal = "Acta hepato-splenologica",
issn = "0172-6390",
publisher = "H.G.E. Update Medical Publishing Ltd.",
number = "52",

}

TY - JOUR

T1 - Gastrointestinal cancer and Herpes zoster in adults

AU - Yamamoto, Manabu

AU - Mine, Hiroyuki

AU - Akazawa, Kohei

AU - Maehara, Yoshihiko

AU - Sugimachi, Keizo

PY - 2003/7/1

Y1 - 2003/7/1

N2 - Background/Aims: Herpes zoster is associated with immunosuppression, and also has an increased risk of malignancy. The aim of this study is to determine whether patients with Herpes zoster are at a higher risk of occult malignancy and gastrointestinal diseases. Methodology: We examined 131 of 201 Japanese patients who showed evidence of Herpes zoster in the gastrointestinal tract including the large intestine using gastrointestinal endoscopy, total colonoscopy and CT scanning. Results: Six of 131 patients (4.6%) with Herpes zoster, who had undergone all three examinations, had malignancies. This rate is significantly higher than the predicted rate (P<0.05). Five of six patients had gastrointestinal or colon cancer. Previously, 17 of the 201 patients has been surgically treated for cancers (17/201=8.5%, predictable rate=8.9%), eleven of these 17 patients had surgery for gastric cancer, or for colon cancer etc. We also diagnosed three patients to have cancers after an episode of Herpes zoster, out of the 140 patients who we examined as study prospects (3/140=2.1%, relative risks=1.75). No significant increases in the malignant rates were observed before or after the onset of Herpes zoster. Conclusions: These findings are considered to support the policy to investigate patients with Herpes zoster for the presence of occult malignancies, though the rate of malignancy in such patients before or after episodes of Herpes zoster was not significantly different from that of the predictable rate.

AB - Background/Aims: Herpes zoster is associated with immunosuppression, and also has an increased risk of malignancy. The aim of this study is to determine whether patients with Herpes zoster are at a higher risk of occult malignancy and gastrointestinal diseases. Methodology: We examined 131 of 201 Japanese patients who showed evidence of Herpes zoster in the gastrointestinal tract including the large intestine using gastrointestinal endoscopy, total colonoscopy and CT scanning. Results: Six of 131 patients (4.6%) with Herpes zoster, who had undergone all three examinations, had malignancies. This rate is significantly higher than the predicted rate (P<0.05). Five of six patients had gastrointestinal or colon cancer. Previously, 17 of the 201 patients has been surgically treated for cancers (17/201=8.5%, predictable rate=8.9%), eleven of these 17 patients had surgery for gastric cancer, or for colon cancer etc. We also diagnosed three patients to have cancers after an episode of Herpes zoster, out of the 140 patients who we examined as study prospects (3/140=2.1%, relative risks=1.75). No significant increases in the malignant rates were observed before or after the onset of Herpes zoster. Conclusions: These findings are considered to support the policy to investigate patients with Herpes zoster for the presence of occult malignancies, though the rate of malignancy in such patients before or after episodes of Herpes zoster was not significantly different from that of the predictable rate.

UR - http://www.scopus.com/inward/record.url?scp=0038338642&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0038338642&partnerID=8YFLogxK

M3 - Article

VL - 50

SP - 1043

EP - 1046

JO - Acta hepato-splenologica

JF - Acta hepato-splenologica

SN - 0172-6390

IS - 52

ER -