Gene transduction by sonoporation

Sho Ohta, Kentaro Suzuki, Yukiko Ogino, Shinichi Miyagawa, Aki Murashima, Daisuke Matsumaru, Gen Yamada

Research output: Contribution to journalShort survey

28 Citations (Scopus)

Abstract

Gene transduction technologies are essential tools for understanding of gene functions or gene cascades underlying embryogenesis. In this review, we introduce a gene transduction method using microbubble and ultrasound (hereafter referred to as sonoporation). Sonoporation is carried out with relatively simple procedures and easily transduces genes into mesenchymal cells without significant damage to target tissues. Therefore, sonoporation is effective for gene transduction to study the molecular mechanisms of morphogenesis.

Original languageEnglish
Pages (from-to)517-520
Number of pages4
JournalDevelopment Growth and Differentiation
Volume50
Issue number6
DOIs
Publication statusPublished - Aug 1 2008
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Developmental Biology
  • Cell Biology

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    Ohta, S., Suzuki, K., Ogino, Y., Miyagawa, S., Murashima, A., Matsumaru, D., & Yamada, G. (2008). Gene transduction by sonoporation. Development Growth and Differentiation, 50(6), 517-520. https://doi.org/10.1111/j.1440-169X.2008.01026.x