Abstract
Copper-catalyzed γ-selective coupling between propargylic phosphates and alkylboron compounds (alkyl-9-BBN, prepared by hydroboration of alkenes with 9-BBN-H) affords multisubstituted allenes with various functional groups. The reaction of enantioenriched propargylic phosphates to give axially chiral allenes proceeds with excellent point-to-axial chirality transfer with 1,3-anti stereochemistry.
Original language | English |
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Pages (from-to) | 6312-6315 |
Number of pages | 4 |
Journal | Organic letters |
Volume | 13 |
Issue number | 23 |
DOIs | |
Publication status | Published - Dec 2 2011 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry