Genes involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide in Streptococcus mutans

Yoshihisa Yamashita, Y. Tsukioka, K. Tomihisa, Y. Nakano, T. Koga

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

We identified in Streptococcus mutans six new genes (rgpA through rgpF), whose disruption results in a loss of serotype-specific antigenicity, specified by the glucose side chains of rhamnose-glucose polysaccharide from the cell wall. Rhamnose and glucose content of the cell wall decreased drastically in all these disruption mutants, except that in the rgpE mutant only the glucose content decreased. RgpC and RgpD are homologous to ATP- binding cassette transporter components and may be involved in polysaccharide export, whereas RgpE may be a transferase of side chain glucose.

Original languageEnglish
Pages (from-to)5803-5807
Number of pages5
JournalJournal of Bacteriology
Volume180
Issue number21
Publication statusPublished - 1998

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Rhamnose
Streptococcus mutans
Cell Wall
Polysaccharides
Glucose
Genes
ATP-Binding Cassette Transporters
Transferases

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Molecular Biology

Cite this

Genes involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide in Streptococcus mutans. / Yamashita, Yoshihisa; Tsukioka, Y.; Tomihisa, K.; Nakano, Y.; Koga, T.

In: Journal of Bacteriology, Vol. 180, No. 21, 1998, p. 5803-5807.

Research output: Contribution to journalArticle

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