Genetic analysis of plasmid-specific pheromone signaling encoded by ppd1 in enterococcus faecalis

Jiro Nakayama, Akinori Suzuki

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

Certain plasmids in Enterococcus faecalis encode a mating response to recipient-produced peptide sex pheromones. Targeted disruption of tra genes on pPD1 suggested that TraA plays a central role in the plasmid-specific pheromone signaling pathway. TraA functioned as a negative regulator for the pheromone-inducible conjugal transfer. Complementation analysis of pPD1 tra gene mutants by pAD1 suggested that the pheromone binding function of TraC was non-specific between these plasmids, but the function of TraA and the pheromone shutdown function of TraB are plasmid-specific.

Original languageEnglish
Pages (from-to)1796-1799
Number of pages4
JournalBioscience, Biotechnology and Biochemistry
Volume61
Issue number11
DOIs
Publication statusPublished - Jan 1997
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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