Genetic variation in experimental dental caries in four inbred strains of rats

T. Kanamoto, K. Nonaka, M. Nakata

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

The relative contribution of the host genetic effect on the susceptibility to dental caries was examined. Four inbred strains of male rats (BN/Sea, F344/Ms, PVG/cSea, and WKA/Sea) were inoculated with Streptococcus mutans and fed a cariogenic diet. The caries scores of the molar teeth were compared among these four strains, and the degree of genetic determination was estimated by analysis of variance. Statistically significant differences in caries scores were found among these strains (F344> WKA>PVG/c>BN), and a high degree of genetic determination was obtained.

Original languageEnglish
Pages (from-to)156-160
Number of pages5
JournalCaries Research
Volume28
Issue number3
DOIs
Publication statusPublished - 1994

All Science Journal Classification (ASJC) codes

  • Dentistry(all)

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