Genetic variation in experimental dental caries in four inbred strains of rats

T. Kanamoto; Kazuaki Nonaka; M. Nakata

doi:10.1159/000261638

Genetic variation in experimental dental caries in four inbred strains of rats

T. Kanamoto, Kazuaki Nonaka, M. Nakata

Oral health, growth and development

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

The relative contribution of the host genetic effect on the susceptibility to dental caries was examined. Four inbred strains of male rats (BN/Sea, F344/Ms, PVG/cSea, and WKA/Sea) were inoculated with Streptococcus mutans and fed a cariogenic diet. The caries scores of the molar teeth were compared among these four strains, and the degree of genetic determination was estimated by analysis of variance. Statistically significant differences in caries scores were found among these strains (F344> WKA>PVG/c>BN), and a high degree of genetic determination was obtained.

Original language	English
Pages (from-to)	156-160
Number of pages	5
Journal	Caries Research
Volume	28
Issue number	3
DOIs	https://doi.org/10.1159/000261638
Publication status	Published - Jan 1 1994

All Science Journal Classification (ASJC) codes

Dentistry(all)

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10.1159/000261638

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abstract = "The relative contribution of the host genetic effect on the susceptibility to dental caries was examined. Four inbred strains of male rats (BN/Sea, F344/Ms, PVG/cSea, and WKA/Sea) were inoculated with Streptococcus mutans and fed a cariogenic diet. The caries scores of the molar teeth were compared among these four strains, and the degree of genetic determination was estimated by analysis of variance. Statistically significant differences in caries scores were found among these strains (F344> WKA>PVG/c>BN), and a high degree of genetic determination was obtained.",

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AU - Nakata, M.

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N2 - The relative contribution of the host genetic effect on the susceptibility to dental caries was examined. Four inbred strains of male rats (BN/Sea, F344/Ms, PVG/cSea, and WKA/Sea) were inoculated with Streptococcus mutans and fed a cariogenic diet. The caries scores of the molar teeth were compared among these four strains, and the degree of genetic determination was estimated by analysis of variance. Statistically significant differences in caries scores were found among these strains (F344> WKA>PVG/c>BN), and a high degree of genetic determination was obtained.

AB - The relative contribution of the host genetic effect on the susceptibility to dental caries was examined. Four inbred strains of male rats (BN/Sea, F344/Ms, PVG/cSea, and WKA/Sea) were inoculated with Streptococcus mutans and fed a cariogenic diet. The caries scores of the molar teeth were compared among these four strains, and the degree of genetic determination was estimated by analysis of variance. Statistically significant differences in caries scores were found among these strains (F344> WKA>PVG/c>BN), and a high degree of genetic determination was obtained.

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