GenomeCons: A web server for manipulating multiple genome sequence alignments and their consensus sequences

Tetsuya Sato, Mikita Suyama

    Research output: Contribution to journalArticle

    3 Citations (Scopus)

    Abstract

    Summary: Genome sequence alignments provide valuable information on many aspects of molecular biological processes. In this study, we developed a web server, GenomeCons, for manipulating multiple genome sequence alignments and their consensus sequences for high-throughput genome sequence analyses. This server facilitates the visual inspection of multiple genome sequence alignments for a set of genomic intervals at a time. This allows the user to examine how these sites are evolutionarily conserved over time for their functional importance. The server also reports consensus sequences for the input genomic intervals, which can be applied to downstream analyses such as the identification of common motifs in the regions determined by ChIP-seq experiments. Availability and implementation: GenomeCons is freely accessible at http://bioinfo.sls.kyushu-u.ac.jp/genomecons/.

    Original languageEnglish
    Pages (from-to)1293-1295
    Number of pages3
    JournalBioinformatics
    Volume31
    Issue number8
    DOIs
    Publication statusPublished - Apr 15 2015

    All Science Journal Classification (ASJC) codes

    • Statistics and Probability
    • Medicine(all)
    • Biochemistry
    • Molecular Biology
    • Computer Science Applications
    • Computational Theory and Mathematics
    • Computational Mathematics

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