GenomeCons: A web server for manipulating multiple genome sequence alignments and their consensus sequences

Tetsuya Sato, Mikita Suyama

    Research output: Contribution to journalArticle

    2 Citations (Scopus)

    Abstract

    Summary: Genome sequence alignments provide valuable information on many aspects of molecular biological processes. In this study, we developed a web server, GenomeCons, for manipulating multiple genome sequence alignments and their consensus sequences for high-throughput genome sequence analyses. This server facilitates the visual inspection of multiple genome sequence alignments for a set of genomic intervals at a time. This allows the user to examine how these sites are evolutionarily conserved over time for their functional importance. The server also reports consensus sequences for the input genomic intervals, which can be applied to downstream analyses such as the identification of common motifs in the regions determined by ChIP-seq experiments. Availability and implementation: GenomeCons is freely accessible at http://bioinfo.sls.kyushu-u.ac.jp/genomecons/.

    Original languageEnglish
    Pages (from-to)1293-1295
    Number of pages3
    JournalBioinformatics
    Volume31
    Issue number8
    DOIs
    Publication statusPublished - Apr 15 2015

    Fingerprint

    Sequence Alignment
    Consensus Sequence
    Web Server
    Genome
    Servers
    Genes
    Genomics
    Server
    Biological Phenomena
    Interval
    High Throughput
    Sequence Analysis
    Inspection
    Chip
    Availability
    Throughput
    Experiment
    Experiments

    All Science Journal Classification (ASJC) codes

    • Statistics and Probability
    • Medicine(all)
    • Biochemistry
    • Molecular Biology
    • Computer Science Applications
    • Computational Theory and Mathematics
    • Computational Mathematics

    Cite this

    GenomeCons : A web server for manipulating multiple genome sequence alignments and their consensus sequences. / Sato, Tetsuya; Suyama, Mikita.

    In: Bioinformatics, Vol. 31, No. 8, 15.04.2015, p. 1293-1295.

    Research output: Contribution to journalArticle

    @article{fbe8f97f609d4660bd440f7d49f80a7b,
    title = "GenomeCons: A web server for manipulating multiple genome sequence alignments and their consensus sequences",
    abstract = "Summary: Genome sequence alignments provide valuable information on many aspects of molecular biological processes. In this study, we developed a web server, GenomeCons, for manipulating multiple genome sequence alignments and their consensus sequences for high-throughput genome sequence analyses. This server facilitates the visual inspection of multiple genome sequence alignments for a set of genomic intervals at a time. This allows the user to examine how these sites are evolutionarily conserved over time for their functional importance. The server also reports consensus sequences for the input genomic intervals, which can be applied to downstream analyses such as the identification of common motifs in the regions determined by ChIP-seq experiments. Availability and implementation: GenomeCons is freely accessible at http://bioinfo.sls.kyushu-u.ac.jp/genomecons/.",
    author = "Tetsuya Sato and Mikita Suyama",
    year = "2015",
    month = "4",
    day = "15",
    doi = "10.1093/bioinformatics/btu803",
    language = "English",
    volume = "31",
    pages = "1293--1295",
    journal = "Bioinformatics",
    issn = "1367-4803",
    publisher = "Oxford University Press",
    number = "8",

    }

    TY - JOUR

    T1 - GenomeCons

    T2 - A web server for manipulating multiple genome sequence alignments and their consensus sequences

    AU - Sato, Tetsuya

    AU - Suyama, Mikita

    PY - 2015/4/15

    Y1 - 2015/4/15

    N2 - Summary: Genome sequence alignments provide valuable information on many aspects of molecular biological processes. In this study, we developed a web server, GenomeCons, for manipulating multiple genome sequence alignments and their consensus sequences for high-throughput genome sequence analyses. This server facilitates the visual inspection of multiple genome sequence alignments for a set of genomic intervals at a time. This allows the user to examine how these sites are evolutionarily conserved over time for their functional importance. The server also reports consensus sequences for the input genomic intervals, which can be applied to downstream analyses such as the identification of common motifs in the regions determined by ChIP-seq experiments. Availability and implementation: GenomeCons is freely accessible at http://bioinfo.sls.kyushu-u.ac.jp/genomecons/.

    AB - Summary: Genome sequence alignments provide valuable information on many aspects of molecular biological processes. In this study, we developed a web server, GenomeCons, for manipulating multiple genome sequence alignments and their consensus sequences for high-throughput genome sequence analyses. This server facilitates the visual inspection of multiple genome sequence alignments for a set of genomic intervals at a time. This allows the user to examine how these sites are evolutionarily conserved over time for their functional importance. The server also reports consensus sequences for the input genomic intervals, which can be applied to downstream analyses such as the identification of common motifs in the regions determined by ChIP-seq experiments. Availability and implementation: GenomeCons is freely accessible at http://bioinfo.sls.kyushu-u.ac.jp/genomecons/.

    UR - http://www.scopus.com/inward/record.url?scp=84927739679&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=84927739679&partnerID=8YFLogxK

    U2 - 10.1093/bioinformatics/btu803

    DO - 10.1093/bioinformatics/btu803

    M3 - Article

    C2 - 25480378

    AN - SCOPUS:84927739679

    VL - 31

    SP - 1293

    EP - 1295

    JO - Bioinformatics

    JF - Bioinformatics

    SN - 1367-4803

    IS - 8

    ER -