Glial Fibrillary Acidic Protein in Tuberous Sclerosis

Mizue Tobo, Yoshio Mitsuyama, Tsunehisa Kaku

Research output: Contribution to journalArticle

Abstract

Abstract: We examined two cases of tuberous sclerosis for the presence of glial fibrillary acidic protein (GFAP) using the immunoperoxidase technique. The majority of abnormal giant cells in the cerebral cortex showed no reaction to anti‐GFAP. Some abnormal cells in the cortical tuber and white matter showed a weak positive reaction. All of the subependymal tumor cells showed no GFAP in their cytoplasm. The abnormal giant cells in tuberous sclerosis,. morphologically similar to gemistocytic astrocyte, are not accompanied by antigenic properties of GFAP.

Original languageEnglish
Pages (from-to)95-100
Number of pages6
JournalPsychiatry and Clinical Neurosciences
Volume37
Issue number1
DOIs
Publication statusPublished - Jan 1 1983

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Tuberous Sclerosis
Glial Fibrillary Acidic Protein
Giant Cells
Immunoenzyme Techniques
Astrocytes
Cerebral Cortex
Cytoplasm
Neoplasms

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Neurology
  • Clinical Neurology
  • Psychiatry and Mental health

Cite this

Glial Fibrillary Acidic Protein in Tuberous Sclerosis. / Tobo, Mizue; Mitsuyama, Yoshio; Kaku, Tsunehisa.

In: Psychiatry and Clinical Neurosciences, Vol. 37, No. 1, 01.01.1983, p. 95-100.

Research output: Contribution to journalArticle

Tobo, Mizue ; Mitsuyama, Yoshio ; Kaku, Tsunehisa. / Glial Fibrillary Acidic Protein in Tuberous Sclerosis. In: Psychiatry and Clinical Neurosciences. 1983 ; Vol. 37, No. 1. pp. 95-100.
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