Global cognitive performance and frailty in non-demented community-dwelling older adults: Findings from the Sasaguri Genkimon Study

Sanmei Chen, Takanori Honda, Kenji Narazaki, Tao Chen, Yu Nofuji, Shuzo Kumagai

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Aim: To investigate the associations of global cognitive performance with frailty and pre-frailty in non-demented community-dwelling older adults. Method: A cross-sectional study was carried out using data from the baseline survey of the Sasaguri Genkimon Study in 2011. The study sample consisted of 1565 older adults with complete data and no evidence of dementia. Global cognitive performance was evaluated using the Montreal Cognitive Assessment (MoCA) and the Mini-Mental State Examination (MMSE). Frailty state was defined using the Cardiovascular Health Study criteria, based on five components: unintentional weight loss, low grip strength, exhaustion, low gait speed and low physical activity. Results: Total MoCA and MMSE scores, and their domain-specific scores decreased across the non-frail, pre-frail and frail groups. Poorer total MoCA and MMSE scores, as well as their domain-specific scores, were associated with the greater likelihood of being frail, but not with pre-frailty after full adjustment. The strength of the association with frailty was greater for total MoCA score than for total MMSE score. Domain-specific scores for visuospatial abilities and attention domains in both of the MoCA and MMSE were consistently associated with the likelihood of pre-frailty and frailty, even after being mutually adjusted for all domains. Conclusions: The MoCA performance is more strongly associated with the odds of frailty than the MMSE performance in the relatively functional and non-demented older adult population. The present findings could contribute to further exploration of possible common pathways that can be targeted in the prevention and management for both of these two conditions.

Original languageEnglish
Pages (from-to)729-736
Number of pages8
JournalGeriatrics and Gerontology International
Volume16
Issue number6
DOIs
Publication statusPublished - Jun 1 2016

Fingerprint

Independent Living
Social Adjustment
Aptitude
Hand Strength
Dementia
Weight Loss
Cross-Sectional Studies
Health
examination
Population
community
performance
performance assessment
Walking Speed
Surveys and Questionnaires
dementia
cross-sectional study
ability
health
management

All Science Journal Classification (ASJC) codes

  • Health(social science)
  • Gerontology
  • Geriatrics and Gerontology

Cite this

Global cognitive performance and frailty in non-demented community-dwelling older adults : Findings from the Sasaguri Genkimon Study. / Chen, Sanmei; Honda, Takanori; Narazaki, Kenji; Chen, Tao; Nofuji, Yu; Kumagai, Shuzo.

In: Geriatrics and Gerontology International, Vol. 16, No. 6, 01.06.2016, p. 729-736.

Research output: Contribution to journalArticle

@article{9fa84eb4f69a47d79ccaf8043e5264eb,
title = "Global cognitive performance and frailty in non-demented community-dwelling older adults: Findings from the Sasaguri Genkimon Study",
abstract = "Aim: To investigate the associations of global cognitive performance with frailty and pre-frailty in non-demented community-dwelling older adults. Method: A cross-sectional study was carried out using data from the baseline survey of the Sasaguri Genkimon Study in 2011. The study sample consisted of 1565 older adults with complete data and no evidence of dementia. Global cognitive performance was evaluated using the Montreal Cognitive Assessment (MoCA) and the Mini-Mental State Examination (MMSE). Frailty state was defined using the Cardiovascular Health Study criteria, based on five components: unintentional weight loss, low grip strength, exhaustion, low gait speed and low physical activity. Results: Total MoCA and MMSE scores, and their domain-specific scores decreased across the non-frail, pre-frail and frail groups. Poorer total MoCA and MMSE scores, as well as their domain-specific scores, were associated with the greater likelihood of being frail, but not with pre-frailty after full adjustment. The strength of the association with frailty was greater for total MoCA score than for total MMSE score. Domain-specific scores for visuospatial abilities and attention domains in both of the MoCA and MMSE were consistently associated with the likelihood of pre-frailty and frailty, even after being mutually adjusted for all domains. Conclusions: The MoCA performance is more strongly associated with the odds of frailty than the MMSE performance in the relatively functional and non-demented older adult population. The present findings could contribute to further exploration of possible common pathways that can be targeted in the prevention and management for both of these two conditions.",
author = "Sanmei Chen and Takanori Honda and Kenji Narazaki and Tao Chen and Yu Nofuji and Shuzo Kumagai",
year = "2016",
month = "6",
day = "1",
doi = "10.1111/ggi.12546",
language = "English",
volume = "16",
pages = "729--736",
journal = "Geriatrics and Gerontology International",
issn = "1447-0594",
publisher = "Japan Geriatrics Society",
number = "6",

}

TY - JOUR

T1 - Global cognitive performance and frailty in non-demented community-dwelling older adults

T2 - Findings from the Sasaguri Genkimon Study

AU - Chen, Sanmei

AU - Honda, Takanori

AU - Narazaki, Kenji

AU - Chen, Tao

AU - Nofuji, Yu

AU - Kumagai, Shuzo

PY - 2016/6/1

Y1 - 2016/6/1

N2 - Aim: To investigate the associations of global cognitive performance with frailty and pre-frailty in non-demented community-dwelling older adults. Method: A cross-sectional study was carried out using data from the baseline survey of the Sasaguri Genkimon Study in 2011. The study sample consisted of 1565 older adults with complete data and no evidence of dementia. Global cognitive performance was evaluated using the Montreal Cognitive Assessment (MoCA) and the Mini-Mental State Examination (MMSE). Frailty state was defined using the Cardiovascular Health Study criteria, based on five components: unintentional weight loss, low grip strength, exhaustion, low gait speed and low physical activity. Results: Total MoCA and MMSE scores, and their domain-specific scores decreased across the non-frail, pre-frail and frail groups. Poorer total MoCA and MMSE scores, as well as their domain-specific scores, were associated with the greater likelihood of being frail, but not with pre-frailty after full adjustment. The strength of the association with frailty was greater for total MoCA score than for total MMSE score. Domain-specific scores for visuospatial abilities and attention domains in both of the MoCA and MMSE were consistently associated with the likelihood of pre-frailty and frailty, even after being mutually adjusted for all domains. Conclusions: The MoCA performance is more strongly associated with the odds of frailty than the MMSE performance in the relatively functional and non-demented older adult population. The present findings could contribute to further exploration of possible common pathways that can be targeted in the prevention and management for both of these two conditions.

AB - Aim: To investigate the associations of global cognitive performance with frailty and pre-frailty in non-demented community-dwelling older adults. Method: A cross-sectional study was carried out using data from the baseline survey of the Sasaguri Genkimon Study in 2011. The study sample consisted of 1565 older adults with complete data and no evidence of dementia. Global cognitive performance was evaluated using the Montreal Cognitive Assessment (MoCA) and the Mini-Mental State Examination (MMSE). Frailty state was defined using the Cardiovascular Health Study criteria, based on five components: unintentional weight loss, low grip strength, exhaustion, low gait speed and low physical activity. Results: Total MoCA and MMSE scores, and their domain-specific scores decreased across the non-frail, pre-frail and frail groups. Poorer total MoCA and MMSE scores, as well as their domain-specific scores, were associated with the greater likelihood of being frail, but not with pre-frailty after full adjustment. The strength of the association with frailty was greater for total MoCA score than for total MMSE score. Domain-specific scores for visuospatial abilities and attention domains in both of the MoCA and MMSE were consistently associated with the likelihood of pre-frailty and frailty, even after being mutually adjusted for all domains. Conclusions: The MoCA performance is more strongly associated with the odds of frailty than the MMSE performance in the relatively functional and non-demented older adult population. The present findings could contribute to further exploration of possible common pathways that can be targeted in the prevention and management for both of these two conditions.

UR - http://www.scopus.com/inward/record.url?scp=84930989150&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84930989150&partnerID=8YFLogxK

U2 - 10.1111/ggi.12546

DO - 10.1111/ggi.12546

M3 - Article

C2 - 26082148

AN - SCOPUS:84930989150

VL - 16

SP - 729

EP - 736

JO - Geriatrics and Gerontology International

JF - Geriatrics and Gerontology International

SN - 1447-0594

IS - 6

ER -