Gonadal and extragonadal functions of Ad4BP/SF-1: Developmental aspects

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Abstract

Gene disruption studies have clearly indicated that 4-binding protein/steroidogenic factor 1 (Ad4BP/SF-1), originally identified as a steroidogenic tissue-specific transcription factor, plays crucial roles in the process of non-steroidogenic as well as steroidogenic tissue differentiation. Although the precise mechanisms underlying differentiation of these tissues are still under investigation, spatial and temporal expression profiles of the gene encoding Ad4BP/SF-1 support its contribution to tissue development from the earliest stages of ontogeny.

Original languageEnglish
Pages (from-to)169-173
Number of pages5
JournalTrends in Endocrinology and Metabolism
Volume10
Issue number5
DOIs
Publication statusPublished - Jul 1 1999
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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