Granular cell tumors of the breast

A report of two cases

Hideya Ohnishi, Kazuyoshi Nishihara, Keiyoshi Tamae, Shoshu Mitsuyama, Ryuji Abe, Satoshi Toyoshima, Eiji Abe

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Granular cell tumors (GCT) are rare neoplasms, and only 173 cases of benign GCT of the breast have been documented. We report herein the cases of two patients with this tumor and discuss the methods of diagnosis and treatment. The first patient was a 60-year-old woman who presented with a firm ill-defined mass in her left breast. Mammography showed a dense shadow with spicula and skin thickness, and ultrasonography revealed a hypoechoic mass with an irregular border. Radical mastectomy was performed tinder the wrong preoperative diagnosis of breast cancer. The second patient was a 31- year-old woman who presented with an elastic-hard mass in her left breast. Mammography showed a well-demarcated dense mass, and ultrasonography revealed a well-defined hypoechoic mass with a large depth-width ratio. Fine-needle aspiration cytology (FNAC) showed a large number of histiocytic cells with abundant granular cytoplasm. An excisional biopsy was performed, and histological examination confirmed a diagnosis of GCT. GCT is benign, but often misdiagnosed as breast cancer both clinically and radiologically. Therefore, histological examination is essential for making a correct diagnosis, while FNAC is also useful. Local resection is still the treatment of choice, and surgeons should do their utmost to avoid performing needless radical mastectomy.

Original languageEnglish
Pages (from-to)929-932
Number of pages4
JournalSurgery today
Volume26
Issue number11
DOIs
Publication statusPublished - Jan 1 1996

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Granular Cell Tumor
Breast
Radical Mastectomy
Mammography
Fine Needle Biopsy
Cell Biology
Ultrasonography
Breast Neoplasms
Diagnostic Errors
Neoplasms
Cytoplasm
Cell Count
Biopsy
Skin
Therapeutics

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

Ohnishi, H., Nishihara, K., Tamae, K., Mitsuyama, S., Abe, R., Toyoshima, S., & Abe, E. (1996). Granular cell tumors of the breast: A report of two cases. Surgery today, 26(11), 929-932. https://doi.org/10.1007/BF00311799

Granular cell tumors of the breast : A report of two cases. / Ohnishi, Hideya; Nishihara, Kazuyoshi; Tamae, Keiyoshi; Mitsuyama, Shoshu; Abe, Ryuji; Toyoshima, Satoshi; Abe, Eiji.

In: Surgery today, Vol. 26, No. 11, 01.01.1996, p. 929-932.

Research output: Contribution to journalArticle

Ohnishi, H, Nishihara, K, Tamae, K, Mitsuyama, S, Abe, R, Toyoshima, S & Abe, E 1996, 'Granular cell tumors of the breast: A report of two cases', Surgery today, vol. 26, no. 11, pp. 929-932. https://doi.org/10.1007/BF00311799
Ohnishi H, Nishihara K, Tamae K, Mitsuyama S, Abe R, Toyoshima S et al. Granular cell tumors of the breast: A report of two cases. Surgery today. 1996 Jan 1;26(11):929-932. https://doi.org/10.1007/BF00311799
Ohnishi, Hideya ; Nishihara, Kazuyoshi ; Tamae, Keiyoshi ; Mitsuyama, Shoshu ; Abe, Ryuji ; Toyoshima, Satoshi ; Abe, Eiji. / Granular cell tumors of the breast : A report of two cases. In: Surgery today. 1996 ; Vol. 26, No. 11. pp. 929-932.
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