Growth behavior of mesenchymal stem cell in 3D porous collagen scaffolds

Takaaki Arahira, Mitsugu Todo, Gouping Chen

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

In this study, porous structures of pure collagen and collagen/β-TCP composite material were developed as scaffolds for bone tissue engineering. Rat bone marrow mesenchymal stem cells (rMSC) were then cultured in the scaffolds with α-MEM based medium and a differentiation supplement. It was found that the compressive moduli of the scaffolds with rMSCs tended to increase with progress of proliferation and differentiation of the cells. Collagen/β-TCP composites were considered to be better scaffold material than pure collagen.

Original languageEnglish
Title of host publicationInterface Oral Health Science 2011
PublisherSpringer Japan
Pages249-251
Number of pages3
ISBN (Electronic)9784431540700
ISBN (Print)9784431540694
DOIs
Publication statusPublished - Jan 1 2012

All Science Journal Classification (ASJC) codes

  • Dentistry(all)

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    Arahira, T., Todo, M., & Chen, G. (2012). Growth behavior of mesenchymal stem cell in 3D porous collagen scaffolds. In Interface Oral Health Science 2011 (pp. 249-251). Springer Japan. https://doi.org/10.1007/978-4-431-54070-0_71