Growth of ring-shaped microtubule assemblies through stepwise active self-organisation

Daisuke Inoue, Arif Md Rashedul Kabir, Hiroyuki Mayama, Jian Ping Gong, Kazuki Sada, Akira Kakugo

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

The microtubule (MT)-kinesin system is a promising candidate for constructing artificial biomachines. The active self-organisation (AcSO) method has been developed to integrate MT filaments into highly organised assembled structures. The creation of ring-shaped MT assemblies is one of the outcomes of the organisation process and holds prospects for use in future nano-technological applications. However, making use of ring-shaped MT assemblies in practical applications requires further control of the size of these assemblies, which has not yet been addressed. In this work, we demonstrated AcSO of MTs in a stepwise manner inside an inert atmosphere. We show that in an inert atmosphere, AcSO could be performed several times (at least nine times), and as a result, this method successfully increased the thickness of ring-shaped MT assemblies.

Original languageEnglish
Pages (from-to)7061-7068
Number of pages8
JournalSoft Matter
Volume9
Issue number29
DOIs
Publication statusPublished - Aug 7 2013
Externally publishedYes

    Fingerprint

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Condensed Matter Physics

Cite this

Inoue, D., Kabir, A. M. R., Mayama, H., Gong, J. P., Sada, K., & Kakugo, A. (2013). Growth of ring-shaped microtubule assemblies through stepwise active self-organisation. Soft Matter, 9(29), 7061-7068. https://doi.org/10.1039/c3sm50704a