Guest-Induced Conformational Change of 6-Monosubstituted Cyclodextrin

Kahee Fujita, Tadashi Ueda, Atsuo Matsunaga, Taiji Imoto

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Flexibly capped cyclodextrins 6-deoxy-6-(3-nitro-4-hydroxy-5-methylphenacylthio)-β-cyclo-dextrin, 6-deoxy-6-(4-pyridyldithio)-β-eyclodextrin, and 6-deoxy-6-(3-carboxy-4-nitrophenyl-dithio)-β-cyclodextrin were prepared in order to detect any conformational change of the host upon guest binding. The changes in the electronic, circular dichroism and/or NMR spectra of there modified cyclodextrins upon binding of several guests indicate conformational changes around the chromophoric moieties of the cyclodextrins. These conformational changes were shown to dependent on the size of the guest molecules. The present modification of β-cyclodextrin enhanced the binding ability of the cyclodextrin.

Original languageEnglish
Pages (from-to)207-213
Number of pages7
JournalNIPPON KAGAKU KAISHI
Volume1983
Issue number2
DOIs
Publication statusPublished - Jan 1 1983

Fingerprint

Cyclodextrins
Dichroism
Nuclear magnetic resonance
Molecules

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)

Cite this

Guest-Induced Conformational Change of 6-Monosubstituted Cyclodextrin. / Fujita, Kahee; Ueda, Tadashi; Matsunaga, Atsuo; Imoto, Taiji.

In: NIPPON KAGAKU KAISHI, Vol. 1983, No. 2, 01.01.1983, p. 207-213.

Research output: Contribution to journalArticle

Fujita, Kahee ; Ueda, Tadashi ; Matsunaga, Atsuo ; Imoto, Taiji. / Guest-Induced Conformational Change of 6-Monosubstituted Cyclodextrin. In: NIPPON KAGAKU KAISHI. 1983 ; Vol. 1983, No. 2. pp. 207-213.
@article{95eec0a6ce1f4b67be2ac2939b62918e,
title = "Guest-Induced Conformational Change of 6-Monosubstituted Cyclodextrin",
abstract = "Flexibly capped cyclodextrins 6-deoxy-6-(3-nitro-4-hydroxy-5-methylphenacylthio)-β-cyclo-dextrin, 6-deoxy-6-(4-pyridyldithio)-β-eyclodextrin, and 6-deoxy-6-(3-carboxy-4-nitrophenyl-dithio)-β-cyclodextrin were prepared in order to detect any conformational change of the host upon guest binding. The changes in the electronic, circular dichroism and/or NMR spectra of there modified cyclodextrins upon binding of several guests indicate conformational changes around the chromophoric moieties of the cyclodextrins. These conformational changes were shown to dependent on the size of the guest molecules. The present modification of β-cyclodextrin enhanced the binding ability of the cyclodextrin.",
author = "Kahee Fujita and Tadashi Ueda and Atsuo Matsunaga and Taiji Imoto",
year = "1983",
month = "1",
day = "1",
doi = "10.1246/nikkashi.1983.207",
language = "English",
volume = "1983",
pages = "207--213",
journal = "Nippon Kagaku Kaishi / Chemical Society of Japan - Chemistry and Industrial Chemistry Journal",
issn = "0369-4577",
publisher = "Chemical Society of Japan",
number = "2",

}

TY - JOUR

T1 - Guest-Induced Conformational Change of 6-Monosubstituted Cyclodextrin

AU - Fujita, Kahee

AU - Ueda, Tadashi

AU - Matsunaga, Atsuo

AU - Imoto, Taiji

PY - 1983/1/1

Y1 - 1983/1/1

N2 - Flexibly capped cyclodextrins 6-deoxy-6-(3-nitro-4-hydroxy-5-methylphenacylthio)-β-cyclo-dextrin, 6-deoxy-6-(4-pyridyldithio)-β-eyclodextrin, and 6-deoxy-6-(3-carboxy-4-nitrophenyl-dithio)-β-cyclodextrin were prepared in order to detect any conformational change of the host upon guest binding. The changes in the electronic, circular dichroism and/or NMR spectra of there modified cyclodextrins upon binding of several guests indicate conformational changes around the chromophoric moieties of the cyclodextrins. These conformational changes were shown to dependent on the size of the guest molecules. The present modification of β-cyclodextrin enhanced the binding ability of the cyclodextrin.

AB - Flexibly capped cyclodextrins 6-deoxy-6-(3-nitro-4-hydroxy-5-methylphenacylthio)-β-cyclo-dextrin, 6-deoxy-6-(4-pyridyldithio)-β-eyclodextrin, and 6-deoxy-6-(3-carboxy-4-nitrophenyl-dithio)-β-cyclodextrin were prepared in order to detect any conformational change of the host upon guest binding. The changes in the electronic, circular dichroism and/or NMR spectra of there modified cyclodextrins upon binding of several guests indicate conformational changes around the chromophoric moieties of the cyclodextrins. These conformational changes were shown to dependent on the size of the guest molecules. The present modification of β-cyclodextrin enhanced the binding ability of the cyclodextrin.

UR - http://www.scopus.com/inward/record.url?scp=85010175432&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85010175432&partnerID=8YFLogxK

U2 - 10.1246/nikkashi.1983.207

DO - 10.1246/nikkashi.1983.207

M3 - Article

VL - 1983

SP - 207

EP - 213

JO - Nippon Kagaku Kaishi / Chemical Society of Japan - Chemistry and Industrial Chemistry Journal

JF - Nippon Kagaku Kaishi / Chemical Society of Japan - Chemistry and Industrial Chemistry Journal

SN - 0369-4577

IS - 2

ER -