Abstract
Flexibly capped cyclodextrins 6-deoxy-6-(3-nitro-4-hydroxy-5-methylphenacylthio)-β-cyclo-dextrin, 6-deoxy-6-(4-pyridyldithio)-β-eyclodextrin, and 6-deoxy-6-(3-carboxy-4-nitrophenyl-dithio)-β-cyclodextrin were prepared in order to detect any conformational change of the host upon guest binding. The changes in the electronic, circular dichroism and/or NMR spectra of there modified cyclodextrins upon binding of several guests indicate conformational changes around the chromophoric moieties of the cyclodextrins. These conformational changes were shown to dependent on the size of the guest molecules. The present modification of β-cyclodextrin enhanced the binding ability of the cyclodextrin.
| Original language | English |
|---|---|
| Pages (from-to) | 207-213 |
| Number of pages | 7 |
| Journal | NIPPON KAGAKU KAISHI |
| Volume | 1983 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Jan 1 1983 |
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All Science Journal Classification (ASJC) codes
- Chemistry(all)
- Chemical Engineering(all)
Cite this
Guest-Induced Conformational Change of 6-Monosubstituted Cyclodextrin. / Fujita, Kahee; Ueda, Tadashi; Matsunaga, Atsuo; Imoto, Taiji.
In: NIPPON KAGAKU KAISHI, Vol. 1983, No. 2, 01.01.1983, p. 207-213.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Guest-Induced Conformational Change of 6-Monosubstituted Cyclodextrin
AU - Fujita, Kahee
AU - Ueda, Tadashi
AU - Matsunaga, Atsuo
AU - Imoto, Taiji
PY - 1983/1/1
Y1 - 1983/1/1
N2 - Flexibly capped cyclodextrins 6-deoxy-6-(3-nitro-4-hydroxy-5-methylphenacylthio)-β-cyclo-dextrin, 6-deoxy-6-(4-pyridyldithio)-β-eyclodextrin, and 6-deoxy-6-(3-carboxy-4-nitrophenyl-dithio)-β-cyclodextrin were prepared in order to detect any conformational change of the host upon guest binding. The changes in the electronic, circular dichroism and/or NMR spectra of there modified cyclodextrins upon binding of several guests indicate conformational changes around the chromophoric moieties of the cyclodextrins. These conformational changes were shown to dependent on the size of the guest molecules. The present modification of β-cyclodextrin enhanced the binding ability of the cyclodextrin.
AB - Flexibly capped cyclodextrins 6-deoxy-6-(3-nitro-4-hydroxy-5-methylphenacylthio)-β-cyclo-dextrin, 6-deoxy-6-(4-pyridyldithio)-β-eyclodextrin, and 6-deoxy-6-(3-carboxy-4-nitrophenyl-dithio)-β-cyclodextrin were prepared in order to detect any conformational change of the host upon guest binding. The changes in the electronic, circular dichroism and/or NMR spectra of there modified cyclodextrins upon binding of several guests indicate conformational changes around the chromophoric moieties of the cyclodextrins. These conformational changes were shown to dependent on the size of the guest molecules. The present modification of β-cyclodextrin enhanced the binding ability of the cyclodextrin.
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U2 - 10.1246/nikkashi.1983.207
DO - 10.1246/nikkashi.1983.207
M3 - Article
VL - 1983
SP - 207
EP - 213
JO - Nippon Kagaku Kaishi / Chemical Society of Japan - Chemistry and Industrial Chemistry Journal
JF - Nippon Kagaku Kaishi / Chemical Society of Japan - Chemistry and Industrial Chemistry Journal
SN - 0369-4577
IS - 2
ER -