Heart rate variability analysis of patients with idiopathic left ventricular outflow tract tachycardia - Role of triggered activity

Eimei Shimoike, Norihiro Ueda, Toru Maruyama, Yoshikazu Kaji, Shozo Kanaya, Takehiko Fujino, Yoshiyuki Niho

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

There have been several reports with respect to idiopathic ventricular tachycardias (VTs) originating from the left ventricular outflow tract (LVOT). A previous report suggested that triggered activity plays a partial role in idiopathic LVOT tachycardia from the electrophysiological as well as the electropharmacological viewpoint. However, the exact role of triggered activity in this type of VT remains unknown. In the present study the relationship of the frequency of premature ventricular contractions (PVCs) and heart rate was examined and heart rate variability (HRV) was analyzed in 2 cases of LVOT tachycardia using 24-h Holter electrocardiographic (ECG) monitoring. The relation between the PVCs frequency and heart rate showed a persistently positive correlation, indicating frequent PVCs as heart rate increased. In HRV analysis, NN50 (%), a time-domain variable of parasympathetic activity, showed no change prior to ventricular arrhythmias. In frequency-domain analysis of HRV, the high frequency (HF) component tended to fall prior to repetitive PVCs and VTs. The ratio of the low frequency to high frequency (LF/HF) components increased prior to single PVCs, repetitive PVCs and VTs. Sympathetic predominance predisposes the genesis of these kinds of arrhythmias originating from the LVOT and it is suggested that triggered activity plays an important role in LVOT tachycardia, at least in its initiation.

Original languageEnglish
Pages (from-to)629-635
Number of pages7
JournalJAPANESE CIRCULATION JOURNAL
Volume63
Issue number8
DOIs
Publication statusPublished - Aug 1999

All Science Journal Classification (ASJC) codes

  • Physiology
  • Cardiology and Cardiovascular Medicine

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