Hepatectomy and marked retention of indocyanine green and bromosulfophtalein

N. Yamanaka, Shuji Shimizu, K. Chijiiwa, K. Nishiyama, H. Noshiro, K. Yamaguchi, M. Tanaka

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

A 61-year-old man was admitted to our hospital with right lateral abdominal pain. The patient had chronic hepatitis type B and type C and was diagnosed as hepatocellular carcinoma in the anterior-superior segment of the liver by ultrasonography and abdominal computed tomography. Although laboratory examinations were within normal limits, the indocyanine green retention rate at 15min was as high as 72.0% and the bromosulfophtalein retention rate at 45min 17.3%. We additionally performed technetium-99m-galactosyl human serum albumin liver scintigraphy and liver biopsy, both of which indicated only mild chronic liver damage, indicating that the liver function is adequate for surgery. After partial hepatectomy, a pathological examination revealed well to moderately differentiated hepatocellular carcinoma with only mild chronic inflammation in adjacent liver tissue. The indocyanine green retention rate at 15min is the best discriminating preoperative test for evaluating hepatic functional reserve, but when marked retention of both indocyanine green and bromosulfophtalein show the discrepancy with normal routine liver function tests, technetium-99m-galactosyl human serum albumin liver scintigraphy and liver biopsy are helpful diagnostic methods for assessing the preoperative hepatic function.

Original languageEnglish
Pages (from-to)1450-1452
Number of pages3
JournalHepato-Gastroenterology
Volume48
Issue number41
Publication statusPublished - Nov 9 2001

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Indocyanine Green
Hepatectomy
Liver
Technetium
Serum Albumin
Radionuclide Imaging
Hepatocellular Carcinoma
Biopsy
Liver Function Tests
Chronic Hepatitis B
Chronic Hepatitis C
Abdominal Pain
Ultrasonography
Tomography
Inflammation

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

Cite this

Yamanaka, N., Shimizu, S., Chijiiwa, K., Nishiyama, K., Noshiro, H., Yamaguchi, K., & Tanaka, M. (2001). Hepatectomy and marked retention of indocyanine green and bromosulfophtalein. Hepato-Gastroenterology, 48(41), 1450-1452.

Hepatectomy and marked retention of indocyanine green and bromosulfophtalein. / Yamanaka, N.; Shimizu, Shuji; Chijiiwa, K.; Nishiyama, K.; Noshiro, H.; Yamaguchi, K.; Tanaka, M.

In: Hepato-Gastroenterology, Vol. 48, No. 41, 09.11.2001, p. 1450-1452.

Research output: Contribution to journalArticle

Yamanaka, N, Shimizu, S, Chijiiwa, K, Nishiyama, K, Noshiro, H, Yamaguchi, K & Tanaka, M 2001, 'Hepatectomy and marked retention of indocyanine green and bromosulfophtalein', Hepato-Gastroenterology, vol. 48, no. 41, pp. 1450-1452.
Yamanaka N, Shimizu S, Chijiiwa K, Nishiyama K, Noshiro H, Yamaguchi K et al. Hepatectomy and marked retention of indocyanine green and bromosulfophtalein. Hepato-Gastroenterology. 2001 Nov 9;48(41):1450-1452.
Yamanaka, N. ; Shimizu, Shuji ; Chijiiwa, K. ; Nishiyama, K. ; Noshiro, H. ; Yamaguchi, K. ; Tanaka, M. / Hepatectomy and marked retention of indocyanine green and bromosulfophtalein. In: Hepato-Gastroenterology. 2001 ; Vol. 48, No. 41. pp. 1450-1452.
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