Hepatectomy based on the tumor hemodynamics for hepatocellular carcinoma

A comparison among the hybrid and pure laparoscopic procedures and open surgery

Shogo Kobayashi, Hiroaki Nagano, Shigeru Marubashi, Koichi Kawamoto, Hiroshi Wada, Hidetoshi Eguchi, Masahiro Tanemura, Koji Umeshita, Yuichiro Doki, Masaki Mori

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Purpose: This study was designed to evaluate the surgical parameters and treatment outcomes of tumor hemodynamics-based pure laparoscopic (PURE) and laparoscopy-assisted (HYBRID) hepatectomy for small hepatocellular carcinoma (HCC) compared with those of open hepatectomy. Methods: Using a prospectively collected database from 1997 to 2011, we analyzed the data of 56 consecutive cases of laparoscopic hepatectomy for HCC (PURE, n = 24; HYBRID, n = 29; HALS, n = 3) from among 102 cases undergoing laparoscopic hepatectomy. We employed 27 cases treated by open hepatectomy during the same period as controls. Results: PURE was associated with lesser blood loss, lower weight of the resected liver, and a shorter skin incision than HYBRID and open hepatectomy [median blood loss (mL): PURE 7, HYBRID 380, Open 450; P < 0.05]. On the other hand, HYBRID hepatectomy was associated with a longer operation time [operation time (min): HYBRID 232, Open 185; P = 0.0226]. The length of hospitalization in the cases treated by PURE and HYBRID hepatectomy was shorter than that in the cases treated by open hepatectomy [length of hospitalization (days): PURE 11, HYBRID 12, Open 17; P < 0.05]. One case each of transfusion and morbidity was recorded in this series. There was no significant difference of the overall (OS) or disease-free survival (DFS) between the patients treated by laparoscopic and open hepatectomy (3-year OS: 100 vs. 100 %; DFS 50 vs. 62 %, respectively). Conclusions: Neither the surgical parameters nor the treatment outcomes of hemodynamics-based laparoscopic hepatectomy were inferior to those of open hepatectomy.

Original languageEnglish
Pages (from-to)610-617
Number of pages8
JournalSurgical endoscopy
Volume27
Issue number2
DOIs
Publication statusPublished - Jan 1 2013

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Hepatectomy
Hepatocellular Carcinoma
Hemodynamics
Neoplasms
Disease-Free Survival
Hospitalization
Laparoscopy
Weight Loss
Databases
Morbidity

All Science Journal Classification (ASJC) codes

  • Surgery

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Hepatectomy based on the tumor hemodynamics for hepatocellular carcinoma : A comparison among the hybrid and pure laparoscopic procedures and open surgery. / Kobayashi, Shogo; Nagano, Hiroaki; Marubashi, Shigeru; Kawamoto, Koichi; Wada, Hiroshi; Eguchi, Hidetoshi; Tanemura, Masahiro; Umeshita, Koji; Doki, Yuichiro; Mori, Masaki.

In: Surgical endoscopy, Vol. 27, No. 2, 01.01.2013, p. 610-617.

Research output: Contribution to journalArticle

Kobayashi, Shogo ; Nagano, Hiroaki ; Marubashi, Shigeru ; Kawamoto, Koichi ; Wada, Hiroshi ; Eguchi, Hidetoshi ; Tanemura, Masahiro ; Umeshita, Koji ; Doki, Yuichiro ; Mori, Masaki. / Hepatectomy based on the tumor hemodynamics for hepatocellular carcinoma : A comparison among the hybrid and pure laparoscopic procedures and open surgery. In: Surgical endoscopy. 2013 ; Vol. 27, No. 2. pp. 610-617.
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abstract = "Purpose: This study was designed to evaluate the surgical parameters and treatment outcomes of tumor hemodynamics-based pure laparoscopic (PURE) and laparoscopy-assisted (HYBRID) hepatectomy for small hepatocellular carcinoma (HCC) compared with those of open hepatectomy. Methods: Using a prospectively collected database from 1997 to 2011, we analyzed the data of 56 consecutive cases of laparoscopic hepatectomy for HCC (PURE, n = 24; HYBRID, n = 29; HALS, n = 3) from among 102 cases undergoing laparoscopic hepatectomy. We employed 27 cases treated by open hepatectomy during the same period as controls. Results: PURE was associated with lesser blood loss, lower weight of the resected liver, and a shorter skin incision than HYBRID and open hepatectomy [median blood loss (mL): PURE 7, HYBRID 380, Open 450; P < 0.05]. On the other hand, HYBRID hepatectomy was associated with a longer operation time [operation time (min): HYBRID 232, Open 185; P = 0.0226]. The length of hospitalization in the cases treated by PURE and HYBRID hepatectomy was shorter than that in the cases treated by open hepatectomy [length of hospitalization (days): PURE 11, HYBRID 12, Open 17; P < 0.05]. One case each of transfusion and morbidity was recorded in this series. There was no significant difference of the overall (OS) or disease-free survival (DFS) between the patients treated by laparoscopic and open hepatectomy (3-year OS: 100 vs. 100 {\%}; DFS 50 vs. 62 {\%}, respectively). Conclusions: Neither the surgical parameters nor the treatment outcomes of hemodynamics-based laparoscopic hepatectomy were inferior to those of open hepatectomy.",
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AU - Kawamoto, Koichi

AU - Wada, Hiroshi

AU - Eguchi, Hidetoshi

AU - Tanemura, Masahiro

AU - Umeshita, Koji

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AU - Mori, Masaki

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AB - Purpose: This study was designed to evaluate the surgical parameters and treatment outcomes of tumor hemodynamics-based pure laparoscopic (PURE) and laparoscopy-assisted (HYBRID) hepatectomy for small hepatocellular carcinoma (HCC) compared with those of open hepatectomy. Methods: Using a prospectively collected database from 1997 to 2011, we analyzed the data of 56 consecutive cases of laparoscopic hepatectomy for HCC (PURE, n = 24; HYBRID, n = 29; HALS, n = 3) from among 102 cases undergoing laparoscopic hepatectomy. We employed 27 cases treated by open hepatectomy during the same period as controls. Results: PURE was associated with lesser blood loss, lower weight of the resected liver, and a shorter skin incision than HYBRID and open hepatectomy [median blood loss (mL): PURE 7, HYBRID 380, Open 450; P < 0.05]. On the other hand, HYBRID hepatectomy was associated with a longer operation time [operation time (min): HYBRID 232, Open 185; P = 0.0226]. The length of hospitalization in the cases treated by PURE and HYBRID hepatectomy was shorter than that in the cases treated by open hepatectomy [length of hospitalization (days): PURE 11, HYBRID 12, Open 17; P < 0.05]. One case each of transfusion and morbidity was recorded in this series. There was no significant difference of the overall (OS) or disease-free survival (DFS) between the patients treated by laparoscopic and open hepatectomy (3-year OS: 100 vs. 100 %; DFS 50 vs. 62 %, respectively). Conclusions: Neither the surgical parameters nor the treatment outcomes of hemodynamics-based laparoscopic hepatectomy were inferior to those of open hepatectomy.

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