Hepatitis C virus infection in institutionalized psychiatric patients: Possible role of transmission by razor sharing

Yasunori Sawayama, Jun Hayashi, Kyoji Kakuda, Norihiro Furusyo, Iwao Ariyama, Yasunobu Kawakami, Naoko Kinukawa, Seizaburo Kashiwagi

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Abstract

The objective of this study was to determine if HCV can be transmitted from patient to patient in psychiatric institutions and to determine possible routes of infection. We did a cross-sectional survey of 196 Japanese psychiatric patients tested for HCV and HBV markers and 400 age- and sex- matched controls. Anti-HCV was detected in 10.2% and antibody to hepatitis B core antigen was detected in 44.4% of the patients, a significantly higher prevalence than found among matched controls. A multiple regression logistic analysis was used to identify risk factors that could indicate the route of infection by HCV. Duration of hospitalization, age, razor sharing, and history of surgery proved to be statistically significant independent risk factors associated with positive anti-HCV results [odds ratio (OR), 4.00; 95% confidence interval (CI), CI, 1.74-9.19; OR, 2.19; 95% CI, 1.27-1.3.77; OR, 4.90; 95% CI, 1.29-18.86; OR, 3.35; 95% CI, 0.997-11.3, respectively]. These observations suggest that razor sharing played an important role in the spread of the HCV infection in the institutionalized psychiatric patients we studied.

Original languageEnglish
Pages (from-to)351-356
Number of pages6
JournalDigestive Diseases and Sciences
Volume45
Issue number2
DOIs
Publication statusPublished - Mar 16 2000

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All Science Journal Classification (ASJC) codes

  • Physiology
  • Gastroenterology

Cite this

Sawayama, Y., Hayashi, J., Kakuda, K., Furusyo, N., Ariyama, I., Kawakami, Y., ... Kashiwagi, S. (2000). Hepatitis C virus infection in institutionalized psychiatric patients: Possible role of transmission by razor sharing. Digestive Diseases and Sciences, 45(2), 351-356. https://doi.org/10.1023/A:1005472812403