Hepatocellular adenoma showing high uptake of 18F-fluorodeoxyglucose (FDG) via an increased expression of glucose transporter 2 (GLUT-2)

Takaaki Nakashima, Yukihisa Takayama, Akihiro Nishie, Yoshiki Asayama, Shingo Baba, Youichi Yamashita, Ken Shirabe, Yuichiro Kubo, Tomoyuki Hida, Hiroshi Honda

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Hepatocellular adenoma (HCA) is a benign liver neoplasm composed of hepatocytes. We experienced HCA demonstrating a high uptake of 18F-fluorodeoxyglucose (FDG) on positron emission tomography-computed tomography, mimicking a malignant tumor. The mechanism underlying the uptake of FDG has not been identified. Here, we discuss that an enhancement of glucose metabolism via an increased expression of glucose transporter 2 may have a role in the high uptake of FDG shown by HCAs.

Original languageEnglish
Pages (from-to)888-891
Number of pages4
JournalClinical Imaging
Volume38
Issue number6
DOIs
Publication statusPublished - Jan 1 2014

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Liver Cell Adenoma
Facilitative Glucose Transport Proteins
Fluorodeoxyglucose F18
Liver Neoplasms
Hepatocytes
Neoplasms
Glucose
Positron Emission Tomography Computed Tomography

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Hepatocellular adenoma showing high uptake of 18F-fluorodeoxyglucose (FDG) via an increased expression of glucose transporter 2 (GLUT-2). / Nakashima, Takaaki; Takayama, Yukihisa; Nishie, Akihiro; Asayama, Yoshiki; Baba, Shingo; Yamashita, Youichi; Shirabe, Ken; Kubo, Yuichiro; Hida, Tomoyuki; Honda, Hiroshi.

In: Clinical Imaging, Vol. 38, No. 6, 01.01.2014, p. 888-891.

Research output: Contribution to journalArticle

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AU - Asayama, Yoshiki

AU - Baba, Shingo

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AU - Shirabe, Ken

AU - Kubo, Yuichiro

AU - Hida, Tomoyuki

AU - Honda, Hiroshi

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