Hepatocellular adenoma showing high uptake of 18F-fluorodeoxyglucose (FDG) via an increased expression of glucose transporter 2 (GLUT-2)

Takaaki Nakashima; Yukihisa Takayama; Akihiro Nishie; Yoshiki Asayama; Shingo Baba; Youichi Yamashita; Ken Shirabe; Yuichiro Kubo; Tomoyuki Hida; Hiroshi Honda

doi:10.1016/j.clinimag.2014.06.005

Hepatocellular adenoma showing high uptake of ¹⁸F-fluorodeoxyglucose (FDG) via an increased expression of glucose transporter 2 (GLUT-2)

Takaaki Nakashima, Yukihisa Takayama, Akihiro Nishie, Yoshiki Asayama, Shingo Baba, Youichi Yamashita, Ken Shirabe, Yuichiro Kubo, Tomoyuki Hida, Hiroshi Honda

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Hepatocellular adenoma (HCA) is a benign liver neoplasm composed of hepatocytes. We experienced HCA demonstrating a high uptake of ¹⁸F-fluorodeoxyglucose (FDG) on positron emission tomography-computed tomography, mimicking a malignant tumor. The mechanism underlying the uptake of FDG has not been identified. Here, we discuss that an enhancement of glucose metabolism via an increased expression of glucose transporter 2 may have a role in the high uptake of FDG shown by HCAs.

Original language	English
Pages (from-to)	888-891
Number of pages	4
Journal	Clinical Imaging
Volume	38
Issue number	6
DOIs	https://doi.org/10.1016/j.clinimag.2014.06.005
Publication status	Published - 2014

All Science Journal Classification (ASJC) codes

Radiology Nuclear Medicine and imaging

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10.1016/j.clinimag.2014.06.005

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title = "Hepatocellular adenoma showing high uptake of 18F-fluorodeoxyglucose (FDG) via an increased expression of glucose transporter 2 (GLUT-2)",

abstract = "Hepatocellular adenoma (HCA) is a benign liver neoplasm composed of hepatocytes. We experienced HCA demonstrating a high uptake of 18F-fluorodeoxyglucose (FDG) on positron emission tomography-computed tomography, mimicking a malignant tumor. The mechanism underlying the uptake of FDG has not been identified. Here, we discuss that an enhancement of glucose metabolism via an increased expression of glucose transporter 2 may have a role in the high uptake of FDG shown by HCAs.",

author = "Takaaki Nakashima and Yukihisa Takayama and Akihiro Nishie and Yoshiki Asayama and Shingo Baba and Youichi Yamashita and Ken Shirabe and Yuichiro Kubo and Tomoyuki Hida and Hiroshi Honda",

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language = "English",

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journal = "Clinical Imaging",

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T1 - Hepatocellular adenoma showing high uptake of 18F-fluorodeoxyglucose (FDG) via an increased expression of glucose transporter 2 (GLUT-2)

AU - Nakashima, Takaaki

AU - Takayama, Yukihisa

AU - Nishie, Akihiro

AU - Asayama, Yoshiki

AU - Baba, Shingo

AU - Yamashita, Youichi

AU - Shirabe, Ken

AU - Kubo, Yuichiro

AU - Hida, Tomoyuki

AU - Honda, Hiroshi

PY - 2014

Y1 - 2014

N2 - Hepatocellular adenoma (HCA) is a benign liver neoplasm composed of hepatocytes. We experienced HCA demonstrating a high uptake of 18F-fluorodeoxyglucose (FDG) on positron emission tomography-computed tomography, mimicking a malignant tumor. The mechanism underlying the uptake of FDG has not been identified. Here, we discuss that an enhancement of glucose metabolism via an increased expression of glucose transporter 2 may have a role in the high uptake of FDG shown by HCAs.

AB - Hepatocellular adenoma (HCA) is a benign liver neoplasm composed of hepatocytes. We experienced HCA demonstrating a high uptake of 18F-fluorodeoxyglucose (FDG) on positron emission tomography-computed tomography, mimicking a malignant tumor. The mechanism underlying the uptake of FDG has not been identified. Here, we discuss that an enhancement of glucose metabolism via an increased expression of glucose transporter 2 may have a role in the high uptake of FDG shown by HCAs.

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JO - Clinical Imaging

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IS - 6

ER -

Hepatocellular adenoma showing high uptake of ¹⁸F-fluorodeoxyglucose (FDG) via an increased expression of glucose transporter 2 (GLUT-2)

Abstract

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