Hepatocellular carcinoma with sarcomatous change

Characteristic findings of two-phased incremental CT

Hiroshi Honda, T. Hayashi, K. Yoshida, K. Takenaka, K. Kaneko, T. Fukuya, Y. Tateshi, T. Ro, T. Maeda, K. Masuda

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Background: Because of its poor prognosis, the diagnosis of hepatocellular carcinoma with sarcomatous change (HCCSC) is clinically important. The purpose of this study is to elucidate the characteristic CT findings of HCCSC. Methods: Two-phased dynamic incremental CT images of six histologically proven HCCSC were retrospectively reviewed. Results: All tumors (100%) exhibited peripheral enhancement on delayed CT images. Lymphadenopathy was observed in 100% (six of six patients); intrahepatic metastases, in 83% (five of six). Both metastatic lesions showed findings similar to those of the primary hepatic tumors, such as peripheral enhancement. Histopathologically, delayed and/or prolonged peripherally enhanced areas consisted of viable cancer cells with sarcomatous changes. Conclusions: The appearance of HCCSC on CT is that of an irregularly demarcated intrahepatic mass with delayed or prolonged peripheral enhancement, frequently with intrahepatic metastases and lymphadenopathy.

Original languageEnglish
Pages (from-to)37-40
Number of pages4
JournalAbdominal Imaging
Volume21
Issue number1
DOIs
Publication statusPublished - Jan 1 1996

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Hepatocellular Carcinoma
Neoplasm Metastasis
Neoplasms
Liver
Lymphadenopathy

All Science Journal Classification (ASJC) codes

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Gastroenterology
  • Urology

Cite this

Honda, H., Hayashi, T., Yoshida, K., Takenaka, K., Kaneko, K., Fukuya, T., ... Masuda, K. (1996). Hepatocellular carcinoma with sarcomatous change: Characteristic findings of two-phased incremental CT. Abdominal Imaging, 21(1), 37-40. https://doi.org/10.1007/s002619900006

Hepatocellular carcinoma with sarcomatous change : Characteristic findings of two-phased incremental CT. / Honda, Hiroshi; Hayashi, T.; Yoshida, K.; Takenaka, K.; Kaneko, K.; Fukuya, T.; Tateshi, Y.; Ro, T.; Maeda, T.; Masuda, K.

In: Abdominal Imaging, Vol. 21, No. 1, 01.01.1996, p. 37-40.

Research output: Contribution to journalArticle

Honda, H, Hayashi, T, Yoshida, K, Takenaka, K, Kaneko, K, Fukuya, T, Tateshi, Y, Ro, T, Maeda, T & Masuda, K 1996, 'Hepatocellular carcinoma with sarcomatous change: Characteristic findings of two-phased incremental CT', Abdominal Imaging, vol. 21, no. 1, pp. 37-40. https://doi.org/10.1007/s002619900006
Honda, Hiroshi ; Hayashi, T. ; Yoshida, K. ; Takenaka, K. ; Kaneko, K. ; Fukuya, T. ; Tateshi, Y. ; Ro, T. ; Maeda, T. ; Masuda, K. / Hepatocellular carcinoma with sarcomatous change : Characteristic findings of two-phased incremental CT. In: Abdominal Imaging. 1996 ; Vol. 21, No. 1. pp. 37-40.
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abstract = "Background: Because of its poor prognosis, the diagnosis of hepatocellular carcinoma with sarcomatous change (HCCSC) is clinically important. The purpose of this study is to elucidate the characteristic CT findings of HCCSC. Methods: Two-phased dynamic incremental CT images of six histologically proven HCCSC were retrospectively reviewed. Results: All tumors (100{\%}) exhibited peripheral enhancement on delayed CT images. Lymphadenopathy was observed in 100{\%} (six of six patients); intrahepatic metastases, in 83{\%} (five of six). Both metastatic lesions showed findings similar to those of the primary hepatic tumors, such as peripheral enhancement. Histopathologically, delayed and/or prolonged peripherally enhanced areas consisted of viable cancer cells with sarcomatous changes. Conclusions: The appearance of HCCSC on CT is that of an irregularly demarcated intrahepatic mass with delayed or prolonged peripheral enhancement, frequently with intrahepatic metastases and lymphadenopathy.",
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T2 - Characteristic findings of two-phased incremental CT

AU - Honda, Hiroshi

AU - Hayashi, T.

AU - Yoshida, K.

AU - Takenaka, K.

AU - Kaneko, K.

AU - Fukuya, T.

AU - Tateshi, Y.

AU - Ro, T.

AU - Maeda, T.

AU - Masuda, K.

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N2 - Background: Because of its poor prognosis, the diagnosis of hepatocellular carcinoma with sarcomatous change (HCCSC) is clinically important. The purpose of this study is to elucidate the characteristic CT findings of HCCSC. Methods: Two-phased dynamic incremental CT images of six histologically proven HCCSC were retrospectively reviewed. Results: All tumors (100%) exhibited peripheral enhancement on delayed CT images. Lymphadenopathy was observed in 100% (six of six patients); intrahepatic metastases, in 83% (five of six). Both metastatic lesions showed findings similar to those of the primary hepatic tumors, such as peripheral enhancement. Histopathologically, delayed and/or prolonged peripherally enhanced areas consisted of viable cancer cells with sarcomatous changes. Conclusions: The appearance of HCCSC on CT is that of an irregularly demarcated intrahepatic mass with delayed or prolonged peripheral enhancement, frequently with intrahepatic metastases and lymphadenopathy.

AB - Background: Because of its poor prognosis, the diagnosis of hepatocellular carcinoma with sarcomatous change (HCCSC) is clinically important. The purpose of this study is to elucidate the characteristic CT findings of HCCSC. Methods: Two-phased dynamic incremental CT images of six histologically proven HCCSC were retrospectively reviewed. Results: All tumors (100%) exhibited peripheral enhancement on delayed CT images. Lymphadenopathy was observed in 100% (six of six patients); intrahepatic metastases, in 83% (five of six). Both metastatic lesions showed findings similar to those of the primary hepatic tumors, such as peripheral enhancement. Histopathologically, delayed and/or prolonged peripherally enhanced areas consisted of viable cancer cells with sarcomatous changes. Conclusions: The appearance of HCCSC on CT is that of an irregularly demarcated intrahepatic mass with delayed or prolonged peripheral enhancement, frequently with intrahepatic metastases and lymphadenopathy.

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