High concentrations of perfluorooctane sulfonate in mucus of tiger puffer fish Takifugu rubripes: a laboratory exposure study

Masato Honda, Akemi Muta, Akinari Shimazaki, Taiki Akasaka, Michiyasu Yoshikuni, Yohei Shimasaki, Yuji Oshima

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Distribution of perfluorooctane sulfonate (PFOS) was investigated in tissues (plasma, blood clot, mucus, skin, liver, muscle, and gonad) of tiger puffer fish Takifugu rubripes. A single dose of PFOS was intraperitoneally injected at 0.1 mg/kg body weight with samples taken over a 14-day period. The highest concentration of PFOS was found in the plasma, 861 ng/mL at 14 days, followed by the mucus, liver, blood clot, gonads, muscles, and skin of fish. A gradual upward trend in PFOS concentration was observed in the mucus and liver whereas there was no change in the plasma, blood clot, gonad, muscle, and skin after the initial increase in PFOS concentrations following injection. No significant trend for estimated total PFOS content in whole body was observed during the experimental period. Relatively high concentrations of PFOS (690 ng/g ww after 14 days) were detected in body surface mucus that continuously oozes from the skin. These results may suggest that mucus is one of the elimination pathways of PFOS in tiger puffer fish.

Original languageEnglish
Pages (from-to)1551-1558
Number of pages8
JournalEnvironmental Science and Pollution Research
Volume25
Issue number2
DOIs
Publication statusPublished - Jan 1 2018

Fingerprint

Takifugu
Tetraodontiformes
mucus
sulfonate
Mucus
Fish
Skin
Liver
Muscle
Blood
fish
Plasmas
skin
Gonads
muscle
Thrombosis
blood
plasma
Muscles
Tissue

All Science Journal Classification (ASJC) codes

  • Environmental Chemistry
  • Pollution
  • Health, Toxicology and Mutagenesis

Cite this

High concentrations of perfluorooctane sulfonate in mucus of tiger puffer fish Takifugu rubripes : a laboratory exposure study. / Honda, Masato; Muta, Akemi; Shimazaki, Akinari; Akasaka, Taiki; Yoshikuni, Michiyasu; Shimasaki, Yohei; Oshima, Yuji.

In: Environmental Science and Pollution Research, Vol. 25, No. 2, 01.01.2018, p. 1551-1558.

Research output: Contribution to journalArticle

@article{55f292146766497c900e51eba2a27930,
title = "High concentrations of perfluorooctane sulfonate in mucus of tiger puffer fish Takifugu rubripes: a laboratory exposure study",
abstract = "Distribution of perfluorooctane sulfonate (PFOS) was investigated in tissues (plasma, blood clot, mucus, skin, liver, muscle, and gonad) of tiger puffer fish Takifugu rubripes. A single dose of PFOS was intraperitoneally injected at 0.1 mg/kg body weight with samples taken over a 14-day period. The highest concentration of PFOS was found in the plasma, 861 ng/mL at 14 days, followed by the mucus, liver, blood clot, gonads, muscles, and skin of fish. A gradual upward trend in PFOS concentration was observed in the mucus and liver whereas there was no change in the plasma, blood clot, gonad, muscle, and skin after the initial increase in PFOS concentrations following injection. No significant trend for estimated total PFOS content in whole body was observed during the experimental period. Relatively high concentrations of PFOS (690 ng/g ww after 14 days) were detected in body surface mucus that continuously oozes from the skin. These results may suggest that mucus is one of the elimination pathways of PFOS in tiger puffer fish.",
author = "Masato Honda and Akemi Muta and Akinari Shimazaki and Taiki Akasaka and Michiyasu Yoshikuni and Yohei Shimasaki and Yuji Oshima",
year = "2018",
month = "1",
day = "1",
doi = "10.1007/s11356-017-0537-6",
language = "English",
volume = "25",
pages = "1551--1558",
journal = "Environmental Science and Pollution Research",
issn = "0944-1344",
publisher = "Springer Science + Business Media",
number = "2",

}

TY - JOUR

T1 - High concentrations of perfluorooctane sulfonate in mucus of tiger puffer fish Takifugu rubripes

T2 - a laboratory exposure study

AU - Honda, Masato

AU - Muta, Akemi

AU - Shimazaki, Akinari

AU - Akasaka, Taiki

AU - Yoshikuni, Michiyasu

AU - Shimasaki, Yohei

AU - Oshima, Yuji

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Distribution of perfluorooctane sulfonate (PFOS) was investigated in tissues (plasma, blood clot, mucus, skin, liver, muscle, and gonad) of tiger puffer fish Takifugu rubripes. A single dose of PFOS was intraperitoneally injected at 0.1 mg/kg body weight with samples taken over a 14-day period. The highest concentration of PFOS was found in the plasma, 861 ng/mL at 14 days, followed by the mucus, liver, blood clot, gonads, muscles, and skin of fish. A gradual upward trend in PFOS concentration was observed in the mucus and liver whereas there was no change in the plasma, blood clot, gonad, muscle, and skin after the initial increase in PFOS concentrations following injection. No significant trend for estimated total PFOS content in whole body was observed during the experimental period. Relatively high concentrations of PFOS (690 ng/g ww after 14 days) were detected in body surface mucus that continuously oozes from the skin. These results may suggest that mucus is one of the elimination pathways of PFOS in tiger puffer fish.

AB - Distribution of perfluorooctane sulfonate (PFOS) was investigated in tissues (plasma, blood clot, mucus, skin, liver, muscle, and gonad) of tiger puffer fish Takifugu rubripes. A single dose of PFOS was intraperitoneally injected at 0.1 mg/kg body weight with samples taken over a 14-day period. The highest concentration of PFOS was found in the plasma, 861 ng/mL at 14 days, followed by the mucus, liver, blood clot, gonads, muscles, and skin of fish. A gradual upward trend in PFOS concentration was observed in the mucus and liver whereas there was no change in the plasma, blood clot, gonad, muscle, and skin after the initial increase in PFOS concentrations following injection. No significant trend for estimated total PFOS content in whole body was observed during the experimental period. Relatively high concentrations of PFOS (690 ng/g ww after 14 days) were detected in body surface mucus that continuously oozes from the skin. These results may suggest that mucus is one of the elimination pathways of PFOS in tiger puffer fish.

UR - http://www.scopus.com/inward/record.url?scp=85032905807&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85032905807&partnerID=8YFLogxK

U2 - 10.1007/s11356-017-0537-6

DO - 10.1007/s11356-017-0537-6

M3 - Article

C2 - 29098580

AN - SCOPUS:85032905807

VL - 25

SP - 1551

EP - 1558

JO - Environmental Science and Pollution Research

JF - Environmental Science and Pollution Research

SN - 0944-1344

IS - 2

ER -