High incidence of subclinical peripheral neuropathy in myelitis with hyperIgEaemia and mite antigen-specific IgE (atopic myelitis): An electrophysiological study

Manabu Osoegawa, Hirofumi Ochi, Takeshi Yamada, Izumi Horiuchi, Hiroyuki Murai, Hirokazu Furuya, Shozo Tobimatsu, Jun Ichi Kira

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objective. To study subclinical involvement of the peripheral nerves in myelitis with hyperIgEaemia and mite antigen-specific IgE (atopic myelitis: AM). Material and Methods. We carried out a nerve conduction study of the median, ulnar, tibial, and sural nerves in 21 patients with AM and in 28 patients with clinically definite or laboratory-supported definite multiple sclerosis (MS). Results. The patients with AM showed a significantly higher frequency of abnormal records than the MS patients in the sensory nerve conduction study (52.4% vs. 14.3%, p=0.0106). The frequency of abnormal records in the motor nerve conduction study in AM patients was twice as high as in MS patients (38.1 % vs. 17.9 %), but the difference was not statistically significant. Abnormality in the F-wave-evoked frequency in the median nerve was also significantly more common in AM patients than in MS patients (57.9% vs. 10.7%, p=0.0016). Conclusions. These findings suggest that subclinical peripheral neuropathy is frequent in patients with AM.

Original languageEnglish
Pages (from-to)684-691
Number of pages8
JournalInternal Medicine
Volume41
Issue number9
DOIs
Publication statusPublished - Sep 1 2002

All Science Journal Classification (ASJC) codes

  • Internal Medicine

Fingerprint Dive into the research topics of 'High incidence of subclinical peripheral neuropathy in myelitis with hyperIgEaemia and mite antigen-specific IgE (atopic myelitis): An electrophysiological study'. Together they form a unique fingerprint.

  • Cite this