High sensitive amperometric detection of glucose using conductive DLC electrode in higher potential region

Kensuke Honda, Akira Nakahara, Hiroshi Naragino, Kohsuke Yoshinaga

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The possibility of a high sensitive amperometric detection of glucose using electrochemically-generated hydroxyl radicals at Ndoped DLC was examined. Flow injection analytical system using N-doped DLC as an electrode of electrochemical detector showed higher performance of glucose detection in a potential region of oxygen evolution (>3.6 V vs. Ag|AgCl). Linear dynamic range was 5 orders of magnitude (1 μM to 10 mM) and theoretical detection limit (S/N = 3) was 1.37 mM at 3.6 V vs. Ag|AgCl. In addition to glucose, linear relations between values of response current and of sample concentration were observed in molecules easily oxidized by OH radicals (ascorbic acid, 2-propanol, ethyl acetate and ethyl acetoacetate). The oxidation of glucose mediated by OH radicals generated at N-doped DLC in higher potential region is included in the mechanism of amperometric glucose detection at N-doped DLC.

Original languageEnglish
Title of host publicationChemical Sensors 10 -and- MEMS/NEMS 10
Pages377-383
Number of pages7
Edition12
DOIs
Publication statusPublished - 2012
Externally publishedYes
EventSymposia on Chemical Sensors 10 - Chemical and Biological Sensors and Analytical Systems and Microfabricated and Nanofabricated Systems for MEMS/NEMS 10 - 222nd ECS Meeting/PRiME 2012 - Honolulu, HI, United States
Duration: Oct 7 2012Oct 12 2012

Publication series

NameECS Transactions
Number12
Volume50
ISSN (Print)1938-5862
ISSN (Electronic)1938-6737

Other

OtherSymposia on Chemical Sensors 10 - Chemical and Biological Sensors and Analytical Systems and Microfabricated and Nanofabricated Systems for MEMS/NEMS 10 - 222nd ECS Meeting/PRiME 2012
CountryUnited States
CityHonolulu, HI
Period10/7/1210/12/12

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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