TY - GEN
T1 - High-speed on-chip mixing using on-demand vortex generationin microstream
AU - Sakuma, Shinya
AU - Kasai, Yusuke
AU - Arai, Fumihito
N1 - Funding Information:
This work was partially supported by JSPS KAKENHI (18H03762), and Grant-in-Aid for JSPS Research Fellow (18J15242).
Publisher Copyright:
Copyright © (2018) by Chemical and Biological Microsystems Society. All rights reserved.
PY - 2018
Y1 - 2018
N2 - We succeeded in high-speed on-chip mixing by generating the vortex at the localized point in a microstream. We show the evaluation results of the mixing time within 500 micro-seconds which was over 100 times faster than the previous active mixing method. We also performed the concentration control of mixed liquid by combining the flow control of the core-shell focused flow. Furthermore, we applied the technique to the segment-mixing by controlling the mixing period. From these results, we confirmed that the on-demand high-speed mixing was achieved. The proposed method will contribute to analyze not only the chemical reaction but also the response of cells to environmental changes.
AB - We succeeded in high-speed on-chip mixing by generating the vortex at the localized point in a microstream. We show the evaluation results of the mixing time within 500 micro-seconds which was over 100 times faster than the previous active mixing method. We also performed the concentration control of mixed liquid by combining the flow control of the core-shell focused flow. Furthermore, we applied the technique to the segment-mixing by controlling the mixing period. From these results, we confirmed that the on-demand high-speed mixing was achieved. The proposed method will contribute to analyze not only the chemical reaction but also the response of cells to environmental changes.
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M3 - Conference contribution
AN - SCOPUS:85079766598
T3 - 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
SP - 2149
EP - 2150
BT - 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
PB - Chemical and Biological Microsystems Society
T2 - 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Y2 - 11 November 2018 through 15 November 2018
ER -