High-throughput and sensitive analysis of 3-monochloropropane-1,2-diol fatty acid esters in edible oils by supercritical fluid chromatography/tandem mass spectrometry

Katsuhito Hori, Atsuki Matsubara, Takato Uchikata, Kazunobu Tsumura, Eiichiro Fukusaki, Takeshi Bamba

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

We have established a high-throughput and sensitive analytical method based on supercritical fluid chromatography (SFC) coupled with triple quadrupole mass spectrometry (QqQ MS) for 3-monochloropropane-1,2-diol (3-MCPD) fatty acid esters in edible oils. All analytes were successfully separated within 9. min without sample purification. The system was precise and sensitive, with a limit of detection less than 0.063. mg/kg. The recovery rate of 3-MCPD fatty acid esters spiked into oil samples was in the range of 62.68-115.23%. Furthermore, several edible oils were tested for analyzing 3-MCPD fatty acid ester profiles. This is the first report on the analysis of 3-MCPD fatty acid esters by SFC/QqQ MS. The developed method will be a powerful tool for investigating 3-MCPD fatty acid esters in edible oils.

Original languageEnglish
Pages (from-to)99-104
Number of pages6
JournalJournal of Chromatography A
Volume1250
DOIs
Publication statusPublished - Aug 10 2012
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

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