Highly enantioselective Baeyer-Villiger oxidation using Zr(salen) complex as catalyst

Akira Watanabe, Tatsuya Uchida, Katsuji Ito, Tsutomu Katsuki

Research output: Contribution to journalArticle

101 Citations (Scopus)

Abstract

(R, R)-Zr(salen) complex was found to serve as an efficient catalyst for asymmetric Baeyer-Villiger oxidation of pro-chiral and racemic ketones using urea·hydrogen peroxide as the terminal oxidant: for example, high enantioselectivity of 87% ee was achieved in the Baeyer-Villiger reaction of 3-phenylcyclobutanone.

Original languageEnglish
Pages (from-to)4481-4485
Number of pages5
JournalTetrahedron Letters
Volume43
Issue number25
DOIs
Publication statusPublished - Jan 1 2002

Fingerprint

Enantioselectivity
Peroxides
Ketones
Oxidants
Oxidation
Catalysts
disalicylaldehyde ethylenediamine

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Highly enantioselective Baeyer-Villiger oxidation using Zr(salen) complex as catalyst. / Watanabe, Akira; Uchida, Tatsuya; Ito, Katsuji; Katsuki, Tsutomu.

In: Tetrahedron Letters, Vol. 43, No. 25, 01.01.2002, p. 4481-4485.

Research output: Contribution to journalArticle

Watanabe, Akira ; Uchida, Tatsuya ; Ito, Katsuji ; Katsuki, Tsutomu. / Highly enantioselective Baeyer-Villiger oxidation using Zr(salen) complex as catalyst. In: Tetrahedron Letters. 2002 ; Vol. 43, No. 25. pp. 4481-4485.
@article{ea7b3be3898b4df1ba90c77a86004e03,
title = "Highly enantioselective Baeyer-Villiger oxidation using Zr(salen) complex as catalyst",
abstract = "(R, R)-Zr(salen) complex was found to serve as an efficient catalyst for asymmetric Baeyer-Villiger oxidation of pro-chiral and racemic ketones using urea·hydrogen peroxide as the terminal oxidant: for example, high enantioselectivity of 87{\%} ee was achieved in the Baeyer-Villiger reaction of 3-phenylcyclobutanone.",
author = "Akira Watanabe and Tatsuya Uchida and Katsuji Ito and Tsutomu Katsuki",
year = "2002",
month = "1",
day = "1",
doi = "10.1016/S0040-4039(02)00831-6",
language = "English",
volume = "43",
pages = "4481--4485",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "25",

}

TY - JOUR

T1 - Highly enantioselective Baeyer-Villiger oxidation using Zr(salen) complex as catalyst

AU - Watanabe, Akira

AU - Uchida, Tatsuya

AU - Ito, Katsuji

AU - Katsuki, Tsutomu

PY - 2002/1/1

Y1 - 2002/1/1

N2 - (R, R)-Zr(salen) complex was found to serve as an efficient catalyst for asymmetric Baeyer-Villiger oxidation of pro-chiral and racemic ketones using urea·hydrogen peroxide as the terminal oxidant: for example, high enantioselectivity of 87% ee was achieved in the Baeyer-Villiger reaction of 3-phenylcyclobutanone.

AB - (R, R)-Zr(salen) complex was found to serve as an efficient catalyst for asymmetric Baeyer-Villiger oxidation of pro-chiral and racemic ketones using urea·hydrogen peroxide as the terminal oxidant: for example, high enantioselectivity of 87% ee was achieved in the Baeyer-Villiger reaction of 3-phenylcyclobutanone.

UR - http://www.scopus.com/inward/record.url?scp=0037124439&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037124439&partnerID=8YFLogxK

U2 - 10.1016/S0040-4039(02)00831-6

DO - 10.1016/S0040-4039(02)00831-6

M3 - Article

AN - SCOPUS:0037124439

VL - 43

SP - 4481

EP - 4485

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 25

ER -