Highly enantioselective hydrogenative desymmetrization of bicyclic imides leading to multiply functionalized chiral cyclic compounds

Masato Ito, Chika Kobayashi, Akio Himizu, Takao Ikariya

Research output: Contribution to journalArticle

57 Citations (Scopus)

Abstract

Highly enantioselective hydrogenative desymmetrization of bicyclic imides has been developed with chiral CpRu(PN) catalysts. The present hydrogenation directly provides stereochemically well-defined cyclic compounds with excellent enantiomeric exessses, which might otherwise require a detour to reach.

Original languageEnglish
Pages (from-to)11414-11415
Number of pages2
JournalJournal of the American Chemical Society
Volume132
Issue number33
DOIs
Publication statusPublished - Aug 25 2010

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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