Highly stereoselective approach to chiral building block possessing three contiguous asymmetric centers. Preparation of four possible diastereomers of β,β′-dimethyl-bis-homoallylic alcohol derivative

Keisuke Suzuki, Eiji Katayama, Katsuhiko Tomooka, Takashi Matsumoto, Gen ichi Tsuchihashi

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

All four diastereomere of chiral alcohol 2 with three contiguous chiral centers were stereoselectively prepared via diastereoselective addition of nucleophiles (crotyl metal or H-) to α-methyl-β,γ-unsaturated carbonyl compounds 1.

Original languageEnglish
Pages (from-to)3707-3710
Number of pages4
JournalTetrahedron Letters
Volume26
Issue number31
DOIs
Publication statusPublished - Jan 1 1985
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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