TY - JOUR
T1 - Histomorphometric assessments of peri-implant bone around ti-nb-sn alloy implants with low young’s modulus
AU - Shiraishi, Naru
AU - Masumoto, Hiroshi
AU - Takahashi, Kenta
AU - Tenkumo, Taichi
AU - Anada, Takahisa
AU - Suzuki, Osamu
AU - Ogawa, Toru
AU - Sasaki, Keiichi
N1 - Funding Information:
This work was supported by a Grant-in-Aid for Scientific Research (No. 25861822) from the Ministry of Education, Culture, Sports, Science and Technology of Japan. The authors are grateful to Shuji HANADA (Institute for Materials Research, Tohoku University) for providing the Ti-Nb-Sn alloy as test samples for this study. This work is a cooperative program (Proposal No. 15G0206 and 16G0207) of the CRDAM-IMR, Tohoku University.
Publisher Copyright:
© 2020, Japanese Society for Dental Materials and Devices. All rights reserved.
PY - 2020
Y1 - 2020
N2 - Many β-Ti alloys have been developed for, and used in, medical devices because of the corrosion resistance, biocompatibility, and exceptionally low Young’s modulus. The aim of the present study was to investigate the histomorphometric aspects of peri-implant bone around Ti-Nb-Sn alloy implants and compare them with those in the case of commercially pure Ti (Ti). Fluorescent morphological observations of ST-2 cells on the substrate were performed and bone morphogenesis around implants in rat femur was evaluated. There was no difference between the cell morphology on Ti and those on the Ti-Nb-Sn alloy during observation for 24 h. A comparison of the Ti-Nb-Sn alloy implant and the Ti implant showed no significant differences between the bone-to-implant contact ratios or the bone fractions. These results suggest that the biological adaptations with Ti-Nb-Sn implants during a healing period are similar to those with Ti. Ti-Nb-Sn is therefore suitable for use in dental implants.
AB - Many β-Ti alloys have been developed for, and used in, medical devices because of the corrosion resistance, biocompatibility, and exceptionally low Young’s modulus. The aim of the present study was to investigate the histomorphometric aspects of peri-implant bone around Ti-Nb-Sn alloy implants and compare them with those in the case of commercially pure Ti (Ti). Fluorescent morphological observations of ST-2 cells on the substrate were performed and bone morphogenesis around implants in rat femur was evaluated. There was no difference between the cell morphology on Ti and those on the Ti-Nb-Sn alloy during observation for 24 h. A comparison of the Ti-Nb-Sn alloy implant and the Ti implant showed no significant differences between the bone-to-implant contact ratios or the bone fractions. These results suggest that the biological adaptations with Ti-Nb-Sn implants during a healing period are similar to those with Ti. Ti-Nb-Sn is therefore suitable for use in dental implants.
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U2 - 10.4012/dmj.2018-376
DO - 10.4012/dmj.2018-376
M3 - Article
C2 - 31666486
AN - SCOPUS:85078866559
SN - 0287-4547
VL - 39
SP - 148
EP - 153
JO - Dental Materials Journal
JF - Dental Materials Journal
IS - 1
ER -