TY - JOUR
T1 - Histopathologic diversity of gastric cancers
T2 - Relationship between enhancement pattern on dynamic contrast-enhanced CT and histological type
AU - Tsurumaru, Daisuke
AU - Miyasaka, Mitsutoshi
AU - Muraki, Toshio
AU - Nishie, Akihiro
AU - Asayama, Yoshiki
AU - Oki, Eiji
AU - Oda, Yoshinao
AU - Honda, Hiroshi
N1 - Funding Information:
This work was supported by JSPS KAKENHI Grant Number 16K10284.
PY - 2017/12
Y1 - 2017/12
N2 - Purpose To evaluate the diagnostic value of contrast-enhanced computed tomography gastrography (CE-CTG) to predict the histological type of gastric cancer. Materials and methods We analyzed 47 consecutive patients with resectable advanced gastric cancer preoperatively evaluated by multiphasic dynamic contrast-enhanced CT. Two radiologists independently reviewed the CT images and they determined the peak enhancement phase, and then measured the CT attenuation value of the gastric lesion for each phase. The histological types of gastric cancers were assigned to three groups as differentiated-type, undifferentiated-type, and mixed-type. We compared the peak enhancement phase of the three types and compared the CT attenuation values in each phase. Results The peak enhancement was significantly different between the three types of gastric cancers for both readers (reader 1, p = 0.001; reader 2, p = 0.009); most of the undifferentiated types had peak enhancement in the delayed phase. The CT attenuation values of undifferentiated type were significantly higher than those of differentiated or mixed type in the delayed phase according to both readers (reader 1, p = 0.002; reader 2, p = 0.004). Conclusion CE-CTG could provide helpful information in diagnosing the histological type of gastric cancers preoperatively.
AB - Purpose To evaluate the diagnostic value of contrast-enhanced computed tomography gastrography (CE-CTG) to predict the histological type of gastric cancer. Materials and methods We analyzed 47 consecutive patients with resectable advanced gastric cancer preoperatively evaluated by multiphasic dynamic contrast-enhanced CT. Two radiologists independently reviewed the CT images and they determined the peak enhancement phase, and then measured the CT attenuation value of the gastric lesion for each phase. The histological types of gastric cancers were assigned to three groups as differentiated-type, undifferentiated-type, and mixed-type. We compared the peak enhancement phase of the three types and compared the CT attenuation values in each phase. Results The peak enhancement was significantly different between the three types of gastric cancers for both readers (reader 1, p = 0.001; reader 2, p = 0.009); most of the undifferentiated types had peak enhancement in the delayed phase. The CT attenuation values of undifferentiated type were significantly higher than those of differentiated or mixed type in the delayed phase according to both readers (reader 1, p = 0.002; reader 2, p = 0.004). Conclusion CE-CTG could provide helpful information in diagnosing the histological type of gastric cancers preoperatively.
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U2 - 10.1016/j.ejrad.2017.10.018
DO - 10.1016/j.ejrad.2017.10.018
M3 - Article
C2 - 29153374
AN - SCOPUS:85032345041
VL - 97
SP - 90
EP - 95
JO - European Journal of Radiology
JF - European Journal of Radiology
SN - 0720-048X
ER -
