Histopathologic diversity of gastric cancers: Relationship between enhancement pattern on dynamic contrast-enhanced CT and histological type

Daisuke Tsurumaru, mitsutoshi miyasaka, Toshio Muraki, Akihiro Nishie, Yoshiki Asayama, Eiji Oki, Yoshinao Oda, Hiroshi Honda

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Purpose To evaluate the diagnostic value of contrast-enhanced computed tomography gastrography (CE-CTG) to predict the histological type of gastric cancer. Materials and methods We analyzed 47 consecutive patients with resectable advanced gastric cancer preoperatively evaluated by multiphasic dynamic contrast-enhanced CT. Two radiologists independently reviewed the CT images and they determined the peak enhancement phase, and then measured the CT attenuation value of the gastric lesion for each phase. The histological types of gastric cancers were assigned to three groups as differentiated-type, undifferentiated-type, and mixed-type. We compared the peak enhancement phase of the three types and compared the CT attenuation values in each phase. Results The peak enhancement was significantly different between the three types of gastric cancers for both readers (reader 1, p = 0.001; reader 2, p = 0.009); most of the undifferentiated types had peak enhancement in the delayed phase. The CT attenuation values of undifferentiated type were significantly higher than those of differentiated or mixed type in the delayed phase according to both readers (reader 1, p = 0.002; reader 2, p = 0.004). Conclusion CE-CTG could provide helpful information in diagnosing the histological type of gastric cancers preoperatively.

Original languageEnglish
Pages (from-to)90-95
Number of pages6
JournalEuropean Journal of Radiology
Volume97
DOIs
Publication statusPublished - Dec 1 2017

Fingerprint

Stomach Neoplasms
Tomography
Stomach

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

@article{49103324ca814c46b6e621e0feedbd38,
title = "Histopathologic diversity of gastric cancers: Relationship between enhancement pattern on dynamic contrast-enhanced CT and histological type",
abstract = "Purpose To evaluate the diagnostic value of contrast-enhanced computed tomography gastrography (CE-CTG) to predict the histological type of gastric cancer. Materials and methods We analyzed 47 consecutive patients with resectable advanced gastric cancer preoperatively evaluated by multiphasic dynamic contrast-enhanced CT. Two radiologists independently reviewed the CT images and they determined the peak enhancement phase, and then measured the CT attenuation value of the gastric lesion for each phase. The histological types of gastric cancers were assigned to three groups as differentiated-type, undifferentiated-type, and mixed-type. We compared the peak enhancement phase of the three types and compared the CT attenuation values in each phase. Results The peak enhancement was significantly different between the three types of gastric cancers for both readers (reader 1, p = 0.001; reader 2, p = 0.009); most of the undifferentiated types had peak enhancement in the delayed phase. The CT attenuation values of undifferentiated type were significantly higher than those of differentiated or mixed type in the delayed phase according to both readers (reader 1, p = 0.002; reader 2, p = 0.004). Conclusion CE-CTG could provide helpful information in diagnosing the histological type of gastric cancers preoperatively.",
author = "Daisuke Tsurumaru and mitsutoshi miyasaka and Toshio Muraki and Akihiro Nishie and Yoshiki Asayama and Eiji Oki and Yoshinao Oda and Hiroshi Honda",
year = "2017",
month = "12",
day = "1",
doi = "10.1016/j.ejrad.2017.10.018",
language = "English",
volume = "97",
pages = "90--95",
journal = "European Journal of Radiology",
issn = "0720-048X",
publisher = "Elsevier Ireland Ltd",

}

TY - JOUR

T1 - Histopathologic diversity of gastric cancers

T2 - Relationship between enhancement pattern on dynamic contrast-enhanced CT and histological type

AU - Tsurumaru, Daisuke

AU - miyasaka, mitsutoshi

AU - Muraki, Toshio

AU - Nishie, Akihiro

AU - Asayama, Yoshiki

AU - Oki, Eiji

AU - Oda, Yoshinao

AU - Honda, Hiroshi

PY - 2017/12/1

Y1 - 2017/12/1

N2 - Purpose To evaluate the diagnostic value of contrast-enhanced computed tomography gastrography (CE-CTG) to predict the histological type of gastric cancer. Materials and methods We analyzed 47 consecutive patients with resectable advanced gastric cancer preoperatively evaluated by multiphasic dynamic contrast-enhanced CT. Two radiologists independently reviewed the CT images and they determined the peak enhancement phase, and then measured the CT attenuation value of the gastric lesion for each phase. The histological types of gastric cancers were assigned to three groups as differentiated-type, undifferentiated-type, and mixed-type. We compared the peak enhancement phase of the three types and compared the CT attenuation values in each phase. Results The peak enhancement was significantly different between the three types of gastric cancers for both readers (reader 1, p = 0.001; reader 2, p = 0.009); most of the undifferentiated types had peak enhancement in the delayed phase. The CT attenuation values of undifferentiated type were significantly higher than those of differentiated or mixed type in the delayed phase according to both readers (reader 1, p = 0.002; reader 2, p = 0.004). Conclusion CE-CTG could provide helpful information in diagnosing the histological type of gastric cancers preoperatively.

AB - Purpose To evaluate the diagnostic value of contrast-enhanced computed tomography gastrography (CE-CTG) to predict the histological type of gastric cancer. Materials and methods We analyzed 47 consecutive patients with resectable advanced gastric cancer preoperatively evaluated by multiphasic dynamic contrast-enhanced CT. Two radiologists independently reviewed the CT images and they determined the peak enhancement phase, and then measured the CT attenuation value of the gastric lesion for each phase. The histological types of gastric cancers were assigned to three groups as differentiated-type, undifferentiated-type, and mixed-type. We compared the peak enhancement phase of the three types and compared the CT attenuation values in each phase. Results The peak enhancement was significantly different between the three types of gastric cancers for both readers (reader 1, p = 0.001; reader 2, p = 0.009); most of the undifferentiated types had peak enhancement in the delayed phase. The CT attenuation values of undifferentiated type were significantly higher than those of differentiated or mixed type in the delayed phase according to both readers (reader 1, p = 0.002; reader 2, p = 0.004). Conclusion CE-CTG could provide helpful information in diagnosing the histological type of gastric cancers preoperatively.

UR - http://www.scopus.com/inward/record.url?scp=85032345041&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85032345041&partnerID=8YFLogxK

U2 - 10.1016/j.ejrad.2017.10.018

DO - 10.1016/j.ejrad.2017.10.018

M3 - Article

C2 - 29153374

AN - SCOPUS:85032345041

VL - 97

SP - 90

EP - 95

JO - European Journal of Radiology

JF - European Journal of Radiology

SN - 0720-048X

ER -