Histopathologic findings of spontaneous osteonecrosis of the knee at an early stage: a case report

Hiroyuki Hatanaka; Takuaki Yamamoto; Goro Motomura; Kazuhiko Sonoda; Yukihide Iwamoto

doi:10.1007/s00256-016-2328-4

Histopathologic findings of spontaneous osteonecrosis of the knee at an early stage: a case report

Hiroyuki Hatanaka, Takuaki Yamamoto, Goro Motomura, Kazuhiko Sonoda, Yukihide Iwamoto

Orthopedic Surgery

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

We histopathologically examined a surgically resected full specimen obtained from an early-stage spontaneous osteonecrosis of the knee (SPONK). On a mid-coronal cut section of the resected medial femoral condyle, a linear fracture line paralleling the subchondral bone endplate was found. Histopathologically, prominent callus formation was seen comprising of reactive woven bone and granulation tissue on both sides of the fracture. Fracture-related bone debris was focally observed at the osteochondral side of the fracture. Definitive features of antecedent bone infarction such as creeping substitution and bone marrow necrosis were not detected. These findings suggested that SPONK was the result of a subchondral fracture rather than primary osteonecrosis.

Original language	English
Pages (from-to)	713-716
Number of pages	4
Journal	Skeletal Radiology
Volume	45
Issue number	5
DOIs	https://doi.org/10.1007/s00256-016-2328-4
Publication status	Published - May 1 2016

All Science Journal Classification (ASJC) codes

Radiology Nuclear Medicine and imaging

Access to Document

10.1007/s00256-016-2328-4

Cite this

@article{9bde9eeee18b4538a7ef620a66d3a198,

title = "Histopathologic findings of spontaneous osteonecrosis of the knee at an early stage: a case report",

abstract = "We histopathologically examined a surgically resected full specimen obtained from an early-stage spontaneous osteonecrosis of the knee (SPONK). On a mid-coronal cut section of the resected medial femoral condyle, a linear fracture line paralleling the subchondral bone endplate was found. Histopathologically, prominent callus formation was seen comprising of reactive woven bone and granulation tissue on both sides of the fracture. Fracture-related bone debris was focally observed at the osteochondral side of the fracture. Definitive features of antecedent bone infarction such as creeping substitution and bone marrow necrosis were not detected. These findings suggested that SPONK was the result of a subchondral fracture rather than primary osteonecrosis.",

author = "Hiroyuki Hatanaka and Takuaki Yamamoto and Goro Motomura and Kazuhiko Sonoda and Yukihide Iwamoto",

note = "Funding Information: This work was partially supported by a Research Grant for Intractable Diseases from Japan Agency for Medical Research and Development, AMED(H26-Itaku(Nan)-Ippan-031), and a research grant from Japan society for the Promotion of Science(15 K10479). Publisher Copyright: {\textcopyright} 2016, ISS.",

year = "2016",

month = may,

day = "1",

doi = "10.1007/s00256-016-2328-4",

language = "English",

volume = "45",

pages = "713--716",

journal = "Skeletal Radiology",

issn = "0364-2348",

publisher = "Springer Verlag",

number = "5",

}

TY - JOUR

T1 - Histopathologic findings of spontaneous osteonecrosis of the knee at an early stage

T2 - a case report

AU - Hatanaka, Hiroyuki

AU - Yamamoto, Takuaki

AU - Motomura, Goro

AU - Sonoda, Kazuhiko

AU - Iwamoto, Yukihide

N1 - Funding Information: This work was partially supported by a Research Grant for Intractable Diseases from Japan Agency for Medical Research and Development, AMED(H26-Itaku(Nan)-Ippan-031), and a research grant from Japan society for the Promotion of Science(15 K10479). Publisher Copyright: © 2016, ISS.

PY - 2016/5/1

Y1 - 2016/5/1

N2 - We histopathologically examined a surgically resected full specimen obtained from an early-stage spontaneous osteonecrosis of the knee (SPONK). On a mid-coronal cut section of the resected medial femoral condyle, a linear fracture line paralleling the subchondral bone endplate was found. Histopathologically, prominent callus formation was seen comprising of reactive woven bone and granulation tissue on both sides of the fracture. Fracture-related bone debris was focally observed at the osteochondral side of the fracture. Definitive features of antecedent bone infarction such as creeping substitution and bone marrow necrosis were not detected. These findings suggested that SPONK was the result of a subchondral fracture rather than primary osteonecrosis.

AB - We histopathologically examined a surgically resected full specimen obtained from an early-stage spontaneous osteonecrosis of the knee (SPONK). On a mid-coronal cut section of the resected medial femoral condyle, a linear fracture line paralleling the subchondral bone endplate was found. Histopathologically, prominent callus formation was seen comprising of reactive woven bone and granulation tissue on both sides of the fracture. Fracture-related bone debris was focally observed at the osteochondral side of the fracture. Definitive features of antecedent bone infarction such as creeping substitution and bone marrow necrosis were not detected. These findings suggested that SPONK was the result of a subchondral fracture rather than primary osteonecrosis.

UR - http://www.scopus.com/inward/record.url?scp=84954324453&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84954324453&partnerID=8YFLogxK

U2 - 10.1007/s00256-016-2328-4

DO - 10.1007/s00256-016-2328-4

M3 - Article

C2 - 26768133

AN - SCOPUS:84954324453

SN - 0364-2348

VL - 45

SP - 713

EP - 716

JO - Skeletal Radiology

JF - Skeletal Radiology

IS - 5

ER -

Histopathologic findings of spontaneous osteonecrosis of the knee at an early stage: a case report

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this