TY - JOUR
T1 - HLA-DQw3 in Japanese summer-type hypersensitivity pneumonitis induced by Trichosporon cutaneum
AU - Ando, M.
AU - Hirayama, K.
AU - Soda, K.
AU - Okubo, R.
AU - Araki, S.
AU - Sasazuki, Takehiko
PY - 1989/1/1
Y1 - 1989/1/1
N2 -
The phenotype of the major histocompatibility complex, loci A, B, C, DR, and DQ, was studied in 66 patients with Japanese summer-type hypersensitivity pneumonitis induced by Trichosporon cutaneum, and the results were compared with those obtained from 472 normal healthy subjects. Our results showed an increase in the frequency of HLA-DQw3 antigen in the patients (66% compared with 49% in the normal healthy control subjects: χ
2
= 5.48, p = 0.018, RR = 1.92), suggesting the importance of the host factors for the generation of this disease. The association between HLA-DQw3 as an immune suppression gene and the disease is discussed.
AB -
The phenotype of the major histocompatibility complex, loci A, B, C, DR, and DQ, was studied in 66 patients with Japanese summer-type hypersensitivity pneumonitis induced by Trichosporon cutaneum, and the results were compared with those obtained from 472 normal healthy subjects. Our results showed an increase in the frequency of HLA-DQw3 antigen in the patients (66% compared with 49% in the normal healthy control subjects: χ
2
= 5.48, p = 0.018, RR = 1.92), suggesting the importance of the host factors for the generation of this disease. The association between HLA-DQw3 as an immune suppression gene and the disease is discussed.
UR - http://www.scopus.com/inward/record.url?scp=0024421655&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0024421655&partnerID=8YFLogxK
U2 - 10.1164/ajrccm/140.4.948
DO - 10.1164/ajrccm/140.4.948
M3 - Article
C2 - 2802380
AN - SCOPUS:0024421655
SN - 1073-449X
VL - 140
SP - 948
EP - 950
JO - American Review of Respiratory Disease
JF - American Review of Respiratory Disease
IS - 4
ER -