HLA-DQw3 in Japanese summer-type hypersensitivity pneumonitis induced by Trichosporon cutaneum

M. Ando, K. Hirayama, K. Soda, R. Okubo, S. Araki, Takehiko Sasazuki

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

The phenotype of the major histocompatibility complex, loci A, B, C, DR, and DQ, was studied in 66 patients with Japanese summer-type hypersensitivity pneumonitis induced by Trichosporon cutaneum, and the results were compared with those obtained from 472 normal healthy subjects. Our results showed an increase in the frequency of HLA-DQw3 antigen in the patients (66% compared with 49% in the normal healthy control subjects: χ 2 = 5.48, p = 0.018, RR = 1.92), suggesting the importance of the host factors for the generation of this disease. The association between HLA-DQw3 as an immune suppression gene and the disease is discussed.

Original languageEnglish
Pages (from-to)948-950
Number of pages3
JournalAmerican Review of Respiratory Disease
Volume140
Issue number4
DOIs
Publication statusPublished - Jan 1 1989
Externally publishedYes

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Trichosporonosis
Trichosporon
Healthy Volunteers
HLA Antigens
Major Histocompatibility Complex
Phenotype
Genes
HLA-DQ3 antigen

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine

Cite this

HLA-DQw3 in Japanese summer-type hypersensitivity pneumonitis induced by Trichosporon cutaneum. / Ando, M.; Hirayama, K.; Soda, K.; Okubo, R.; Araki, S.; Sasazuki, Takehiko.

In: American Review of Respiratory Disease, Vol. 140, No. 4, 01.01.1989, p. 948-950.

Research output: Contribution to journalArticle

Ando, M. ; Hirayama, K. ; Soda, K. ; Okubo, R. ; Araki, S. ; Sasazuki, Takehiko. / HLA-DQw3 in Japanese summer-type hypersensitivity pneumonitis induced by Trichosporon cutaneum. In: American Review of Respiratory Disease. 1989 ; Vol. 140, No. 4. pp. 948-950.
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