Honeycomb-type retinal device using chemically derived iridium oxide biointerfaces

Kuang Chih Tso, Yuki Fukunari, Mizuki Hagita, Makito Haruta, Hironari Takehara, Hiroyuki Tashiro, Kiyotaka Sasagawa, Pu Wei Wu, Jun Ohta

Research output: Contribution to journalArticlepeer-review

Abstract

Long-term operational stability and high-efficiency neuron stimulation are key to the development of retinal prostheses. In this research, a retinal device with a chemically inert and flexible substrate is introduced, which satisfies these requirements. We have developed a honeycomb-type retinal device that has a high-performance electrode for suprachoroidal transretinal stimulation. The device structure, in which conjunctional bioceramic substrates are embedded with large numbers of stimulating electrodes, provides high-resolution electrical stimulation. The custom CMOS microchip precisely controls the stimulation delivery of the electrodes to initiate artificial vision, offering a partial remedy for retinal ophthalmic diseases. The CMOS chip design was optimized to drastically reduce the number of input wirings. A high-performance stimulating electrode based on iridium oxide was fabricated using a unique solution process called chemical bath deposition (CBD). The honeycomb-type retinal device, equipped with CBD-derived iridium oxide electrodes, was used to evaluate the electrodes’ and device’s performances in vitro.

Original languageEnglish
Article number095305
JournalAIP Advances
Volume11
Issue number9
DOIs
Publication statusPublished - Sep 1 2021

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)

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