How to diagnose polysulphide poisoning from tissue samples

T. Nagata, S. Kage, K. Kimura, K. Kudo, T. Imamura

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

We carried out animal experiments to toxicologically verify polysulphide poisoning by analyzing tissue samples. A bathing agent containing calcium polysulphides was administered orally to rats, and then polysulphides and sulphide, the decomposed product of polysulphides, were analyzed by GC and GC/MS. The concentrations of polysulphides (μmol/ml or g) were found to be highest in blood (0.196), followed by the liver (0.051), the lungs (0.018) and kindneys (0.013), but were below the detection limit (0.005 μmol/g) in the other tissues tested. Sulphide was detected in all the tissue samples and was found to be highest in the blood (0.518 μmol/ml), this being 40 times higher than that required for fatal poisoning in the case of hydrogen sulphide. Polysulphide poisoning was considered to be confirmatively diagnosed by detecting and measuring polysuphides and supplementarily sulphide in body tissues, most pertinently in the blood. Two practical cases of suspected poisoning by polysulphides are briefly described.

Original languageEnglish
Pages (from-to)288-290
Number of pages3
JournalInternational Journal of Legal Medicine
Volume106
Issue number6
DOIs
Publication statusPublished - Nov 1 1994

Fingerprint

Poisoning
Sulfides
Hydrogen Sulfide
Limit of Detection
polysulfide
Lung
Liver

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine

Cite this

How to diagnose polysulphide poisoning from tissue samples. / Nagata, T.; Kage, S.; Kimura, K.; Kudo, K.; Imamura, T.

In: International Journal of Legal Medicine, Vol. 106, No. 6, 01.11.1994, p. 288-290.

Research output: Contribution to journalArticle

Nagata, T, Kage, S, Kimura, K, Kudo, K & Imamura, T 1994, 'How to diagnose polysulphide poisoning from tissue samples', International Journal of Legal Medicine, vol. 106, no. 6, pp. 288-290. https://doi.org/10.1007/BF01224772
Nagata, T. ; Kage, S. ; Kimura, K. ; Kudo, K. ; Imamura, T. / How to diagnose polysulphide poisoning from tissue samples. In: International Journal of Legal Medicine. 1994 ; Vol. 106, No. 6. pp. 288-290.
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