Abstract
Baroreflex regulates arterial pressure by modulating ventricular and vascular properties. We investigated if the framework of circulatory equilibrium that we developed previously (Am J Physiol 2004, 2005) by extending the classic Guyton's framework is capable of predicting baroreflex induced changes in arterial pressure. In animal experiments, we estimated open loop transfer functions of baroreflexly modulated ventricular and vascular properties, synthesized baroreflex induced dynamic changes in arterial pressure using the estimated transfer functions and compared the predicted responses with measured responses. We demonstrated that the predicted baroreflex induced changes in arterial pressure matched reasonable well with those measured. We conclude that the framework of circulatory equilibrium is generalizable under the condition where baroreflex dynamically changes arterial pressure.
| Original language | English |
|---|---|
| Title of host publication | 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 |
| Pages | 2869-2871 |
| Number of pages | 3 |
| DOIs | |
| Publication status | Published - Dec 1 2010 |
| Event | 2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 - Buenos Aires, Argentina Duration: Aug 31 2010 → Sep 4 2010 |
Other
| Other | 2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 |
|---|---|
| Country | Argentina |
| City | Buenos Aires |
| Period | 8/31/10 → 9/4/10 |
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All Science Journal Classification (ASJC) codes
- Biomedical Engineering
- Computer Vision and Pattern Recognition
- Signal Processing
- Health Informatics
Cite this
How to quantitatively synthesize dynamic changes in arterial pressure from baroreflexly modulated ventricular and arterial properties. / sakamoto, takafumi; Murayama, Yoshinori; Tobushi, Tomoyuki; Sakamoto, Kazuo; Tanaka, Atsushi; Tsutsumi, Takaki; Sunagawa, Kenji.
2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10. 2010. p. 2869-2871 5626358.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - How to quantitatively synthesize dynamic changes in arterial pressure from baroreflexly modulated ventricular and arterial properties
AU - sakamoto, takafumi
AU - Murayama, Yoshinori
AU - Tobushi, Tomoyuki
AU - Sakamoto, Kazuo
AU - Tanaka, Atsushi
AU - Tsutsumi, Takaki
AU - Sunagawa, Kenji
PY - 2010/12/1
Y1 - 2010/12/1
N2 - Baroreflex regulates arterial pressure by modulating ventricular and vascular properties. We investigated if the framework of circulatory equilibrium that we developed previously (Am J Physiol 2004, 2005) by extending the classic Guyton's framework is capable of predicting baroreflex induced changes in arterial pressure. In animal experiments, we estimated open loop transfer functions of baroreflexly modulated ventricular and vascular properties, synthesized baroreflex induced dynamic changes in arterial pressure using the estimated transfer functions and compared the predicted responses with measured responses. We demonstrated that the predicted baroreflex induced changes in arterial pressure matched reasonable well with those measured. We conclude that the framework of circulatory equilibrium is generalizable under the condition where baroreflex dynamically changes arterial pressure.
AB - Baroreflex regulates arterial pressure by modulating ventricular and vascular properties. We investigated if the framework of circulatory equilibrium that we developed previously (Am J Physiol 2004, 2005) by extending the classic Guyton's framework is capable of predicting baroreflex induced changes in arterial pressure. In animal experiments, we estimated open loop transfer functions of baroreflexly modulated ventricular and vascular properties, synthesized baroreflex induced dynamic changes in arterial pressure using the estimated transfer functions and compared the predicted responses with measured responses. We demonstrated that the predicted baroreflex induced changes in arterial pressure matched reasonable well with those measured. We conclude that the framework of circulatory equilibrium is generalizable under the condition where baroreflex dynamically changes arterial pressure.
UR - http://www.scopus.com/inward/record.url?scp=78650846801&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78650846801&partnerID=8YFLogxK
U2 - 10.1109/IEMBS.2010.5626358
DO - 10.1109/IEMBS.2010.5626358
M3 - Conference contribution
C2 - 21095975
AN - SCOPUS:78650846801
SN - 9781424441235
SP - 2869
EP - 2871
BT - 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
ER -