Abstract
Baroreflex regulates arterial pressure by modulating ventricular and vascular properties. We investigated if the framework of circulatory equilibrium that we developed previously (Am J Physiol 2004, 2005) by extending the classic Guyton's framework is capable of predicting baroreflex induced changes in arterial pressure. In animal experiments, we estimated open loop transfer functions of baroreflexly modulated ventricular and vascular properties, synthesized baroreflex induced dynamic changes in arterial pressure using the estimated transfer functions and compared the predicted responses with measured responses. We demonstrated that the predicted baroreflex induced changes in arterial pressure matched reasonable well with those measured. We conclude that the framework of circulatory equilibrium is generalizable under the condition where baroreflex dynamically changes arterial pressure.
Original language | English |
---|---|
Title of host publication | 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 |
Pages | 2869-2871 |
Number of pages | 3 |
DOIs | |
Publication status | Published - Dec 1 2010 |
Event | 2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 - Buenos Aires, Argentina Duration: Aug 31 2010 → Sep 4 2010 |
Other
Other | 2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 |
---|---|
Country | Argentina |
City | Buenos Aires |
Period | 8/31/10 → 9/4/10 |
All Science Journal Classification (ASJC) codes
- Biomedical Engineering
- Computer Vision and Pattern Recognition
- Signal Processing
- Health Informatics