Human recombinant granulocyte colony-stimulating factor for the treatment of autoimmune neutropenia

Kazuhiro Takahashi, Shuichi Taniguchi, Koichi Akashi, Kazuma Fujimoto, Tunefumi Sibuya, Hiromi Ishibashi, Mine Harada, Yoshiyuki Niho

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Abstract

We have recently treated a case of autoimmune neutropenia in a 57-year-old male. Because neutropenia persisted despite the administration of prednisolone for 30 days, daily subcutaneous injection of human recombinant granulocyte colony-stimulating factor (rhG-CSF) at a dosage of 100 ug was started. Neutrophil count increased gradually and reached a plateau of 5,000/ul by day 25 after administration of rhG-CSF. This observation suggests that rhG-CSF is effective for the treatment of autoimmune neutropenia.

Original languageEnglish
Pages (from-to)95-98
Number of pages4
JournalActa Haematologica
Volume86
Issue number2
DOIs
Publication statusPublished - Jan 1 1991

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All Science Journal Classification (ASJC) codes

  • Hematology

Cite this

Takahashi, K., Taniguchi, S., Akashi, K., Fujimoto, K., Sibuya, T., Ishibashi, H., ... Niho, Y. (1991). Human recombinant granulocyte colony-stimulating factor for the treatment of autoimmune neutropenia. Acta Haematologica, 86(2), 95-98. https://doi.org/10.1159/000204811