Human serum and particulate debris: Protein binding and macrophage activation

D. H. Sun, Y. Nakashima, W. J. Maloney, S. B. Goodman, D. J. Schurman, R. L. Smith

Research output: Contribution to conferencePaperpeer-review

Abstract

The mechanisms by which particulate debris stimulates periprosthetic bone resorption or osteolysis were studied by examining the extent of serum protein binding to TiAlV and polymethylmethacrylate (PMMA) particles obtained from soft tissue membranes which were harvested during revision surgery. Results show that both TiAlV and PMMA particles are effective in activating macrophages, thereby contributing to the loosening of prosthetics.

Original languageEnglish
Number of pages1
Publication statusPublished - 1996
Externally publishedYes
EventProceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2) - Toronto, Can
Duration: May 29 1996Jun 2 1996

Other

OtherProceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2)
CityToronto, Can
Period5/29/966/2/96

All Science Journal Classification (ASJC) codes

  • Materials Science(all)

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