Hydroarylation of acetylenes, acrylates, and isocyanates with heteroaromatic compounds under rhenium catalysis

Yoichiro Kuninobu, Kou Kikuchi, Yukimi Tokunaga, Yuta Nishina, Kazuhiko Takai

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71 Citations (Scopus)


With the aid of a directing group, an imine moiety, heteroaromatic compounds add to acetylenes in the presence of a catalytic amount of [ReBr(CO)3(THF)]2 at the adjacent position of the directing group regioselectively to give hydroarylation of the acetylenes in good to excellent yields. Similarly, heteroaromatic compounds react with acrylates and isocyanates to give the corresponding hydroarylation products under rhenium catalysis.

Original languageEnglish
Pages (from-to)5974-5981
Number of pages8
Issue number26
Publication statusPublished - Jun 23 2008
Externally publishedYes


All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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