Abstract
The meta-selective introduction of functional groups into aromatic substrates was successfully achieved by hydrogen-bond-controlled meta-selective C-H borylation and successive conversion of the boryl group to other functional groups. By this method a wide range of functional groups could be introduced without isolation of the borylated intermediates. The desired meta-functionalized aromatic products were obtained in a one-pot manner even on a gram scale. Regioselective synthesis of multisubstituted aromatic compounds was also achieved.
| Original language | English |
|---|---|
| Pages (from-to) | 1342-1346 |
| Number of pages | 5 |
| Journal | Organic Letters |
| Volume | 21 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Mar 1 2019 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
Cite this
Hydrogen-Bond-Controlled Formal Meta-Selective C-H Transformations and Regioselective Synthesis of Multisubstituted Aromatic Compounds. / Wang, Jie; Torigoe, Takeru; Kuninobu, Yoichiro.
In: Organic Letters, Vol. 21, No. 5, 01.03.2019, p. 1342-1346.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Hydrogen-Bond-Controlled Formal Meta-Selective C-H Transformations and Regioselective Synthesis of Multisubstituted Aromatic Compounds
AU - Wang, Jie
AU - Torigoe, Takeru
AU - Kuninobu, Yoichiro
PY - 2019/3/1
Y1 - 2019/3/1
N2 - The meta-selective introduction of functional groups into aromatic substrates was successfully achieved by hydrogen-bond-controlled meta-selective C-H borylation and successive conversion of the boryl group to other functional groups. By this method a wide range of functional groups could be introduced without isolation of the borylated intermediates. The desired meta-functionalized aromatic products were obtained in a one-pot manner even on a gram scale. Regioselective synthesis of multisubstituted aromatic compounds was also achieved.
AB - The meta-selective introduction of functional groups into aromatic substrates was successfully achieved by hydrogen-bond-controlled meta-selective C-H borylation and successive conversion of the boryl group to other functional groups. By this method a wide range of functional groups could be introduced without isolation of the borylated intermediates. The desired meta-functionalized aromatic products were obtained in a one-pot manner even on a gram scale. Regioselective synthesis of multisubstituted aromatic compounds was also achieved.
UR - http://www.scopus.com/inward/record.url?scp=85061556247&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85061556247&partnerID=8YFLogxK
U2 - 10.1021/acs.orglett.9b00030
DO - 10.1021/acs.orglett.9b00030
M3 - Article
C2 - 30735396
AN - SCOPUS:85061556247
VL - 21
SP - 1342
EP - 1346
JO - Organic Letters
JF - Organic Letters
SN - 1523-7060
IS - 5
ER -