Hydrogen-bonded dioxygen adduct of an iron porphyrin with an alkanethiolate ligand: An elaborate model of cytochrome P450

Mikiya Matsu-Ura, Fumito Tani, Shinya Nakayama, Nobuhumi Nakamura, Yoshinori Naruta

Research output: Contribution to journalArticlepeer-review

46 Citations (Scopus)

Abstract

A stable dioxygen adduct is formed from a synthetic analogue for cytochrome P450, which has an alkanethiolate ligand and hydroxyl groups inside the molecular cavities (see scheme). The structure exhibits the first clear evidence for a hydrogen bond to bound dioxygen among thiolate- coordinated hemes, including the enzymes.

Original languageEnglish
Pages (from-to)1989-1991
Number of pages3
JournalAngewandte Chemie - International Edition
Volume39
Issue number11
DOIs
Publication statusPublished - Jun 2 2000

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

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