A stable dioxygen adduct is formed from a synthetic analogue for cytochrome P450, which has an alkanethiolate ligand and hydroxyl groups inside the molecular cavities (see scheme). The structure exhibits the first clear evidence for a hydrogen bond to bound dioxygen among thiolate- coordinated hemes, including the enzymes.
|Number of pages||3|
|Journal||Angewandte Chemie - International Edition|
|Publication status||Published - Jun 2 2000|
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