Abstract
The rapid hydrogenation of simple aromatic ketones is accomplished by using a combination of (η5-C5(CH3)5)Ru complexes and primary amines as a catalyst in 2-propanol. In particular, 1,2-diamines with primary and tertiary amino groups at both ends exhibit a significant ligand acceleration effect. Isotope-labeling experiments using D2 and 2-propanol-dn reveal that 2-propanol participates in the activation of H2 based on a metal/NH bifunctional effect to facilitate the hydrogenation. Asymmetric hydrogenation of prochiral simple ketones with the chiral version of the catalysts provides optically active secondary alcohols with up to 95% ee.
Original language | English |
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Pages (from-to) | 379-381 |
Number of pages | 3 |
Journal | Organometallics |
Volume | 20 |
Issue number | 3 |
DOIs | |
Publication status | Published - Feb 5 2001 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Physical and Theoretical Chemistry
- Organic Chemistry
- Inorganic Chemistry