Hydrosilane reduction of tertiary carboxamides by iron carbonyl catalysts

Yusuke Sunada, Hiroko Kawakami, Tsuyoshi Imaoka, Yukihiro Motoyama, Hideo Nagashima

Research output: Contribution to journalArticle

171 Citations (Scopus)

Abstract

Fox in the carboxamide: Reduction of tertiary carboxamides to their corresponding amines is catalyzed by [Fe(CO)5] or [Fe 3(CO)12], using 1,1,3,3tetramethyldlsiloxane (TMDS) as the reducing agent. The reaction proceeds under either thermal or photochemical conditions. Unlike the hydrosilane reduction of amides using platinum or ruthenlum catalysts, TMDS preferentially reduces a nitro group, even in the presence of competing amides.

Original languageEnglish
Pages (from-to)9511-9514
Number of pages4
JournalAngewandte Chemie - International Edition
Volume48
Issue number50
DOIs
Publication statusPublished - Dec 7 2009

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All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

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