A triruthenium cluster, (μ 3, η 2, η 3, η 5-acenaphthylene)Ru 3(CO) 7 effectively catalyzes primary-alkylation reaction of electron-rich aromatic rings using a combination of hydrosilane and ester as a source of the primary-alkyl group. The reaction involves electrophilic substitution of arenes by carbocationic species stabilized by a neighboring alkoxy or siloxy group generated during the reduction of esters giving alkylated arenes after reductive removal of the alkoxy or siloxy group at the benzylic position.
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry