Hypercoagulopathy after repeated injection of 5% ethanolamine oleate to sclerose esophageal varices

M. Hashizume, H. Yamaga, S. Kitano, K. Sugimachi

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6 Citations (Scopus)

Abstract

Hematological and coagulating parameters were examined in 53 patients in an attempt to find possible evidence of disseminated intravascular coagulation after intravascular injection of 5% ethanolamine oleate to sclerose esophageal varices. FDP-E in the peripheral blood measured by latex photometric immunoassay significantly increased from 111.2 ± 112.9 to 234.2 ± 178.3 ng/ml and 370.4 ± 189.5 ng/ml one hour after the first and second sessions of sclerotherapy, respectively (p < 0.01). The other parameters showed no significant change, except on the first day after sclerotherapy. The increase of FDP-E was closely related to fibrinopeptide A (r = 0.689, p < 0.01) and fibrinogen (r = 0.585, p < 0.05), before the sclerotherapy. As repeated intravariceal sclerotherapy over short time intervals can lead to a deterioration of the coagulating system, especially in patients with abnormal preoperative coagulopathy, latex photometric immunoassay for FDP-E is a rapid and useful method of monitoring alterations in the coagulating system.

Original languageEnglish
Pages (from-to)565-568
Number of pages4
JournalHepato-gastroenterology
Volume37
Issue number6
Publication statusPublished - Dec 1 1990

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

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    Hashizume, M., Yamaga, H., Kitano, S., & Sugimachi, K. (1990). Hypercoagulopathy after repeated injection of 5% ethanolamine oleate to sclerose esophageal varices. Hepato-gastroenterology, 37(6), 565-568.