Hyperthermia for rectal cancer

Shinji Ohno, Yasushi Sumiyoshi, Masaki Mori, Keizo Sugimachi

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Bachground. In order to improve the clinical results of rectal cancer, hyperthermia has been prescribed in combination with chemotherapy and radiotherapy. The techniques of hyperthermia and their clinical applications to rectal cancer were reviewed. Methods. The development of heating devices has been intensively investigated, including external heating devices, intraluminal heating devices, circulation of warmed saline solution, and whole body hyperthermia. Results. Nonrandomized and randomized trials for rectal cancer have demonstrated an improved local response with the combined use of hyperthermia and conventional treatments. A preoperative therapy with hyperthermia increased resectability and decreased local recurrence, resulting in the improvement of the postoperative prognosis. There were no major postoperative complications related to the preoperative treatment. A lower incidence of local recurrence was observed in groups that underwent intra- or postoperative hyperthermia treatment, as compared with control groups. In cases with unresectable or local recurrent rectal cancer, hyperthermia achieved a local tumor regression and prolonged pain relief. Conclusions. These clinical data suggest that hyperthermia combined with radiation or chemotherapy demonstrates great promise for the treatment of patients with carcinoma of the rectum.

Original languageEnglish
Pages (from-to)S121-S127
JournalSurgery
Volume131
Issue number1
DOIs
Publication statusPublished - Jan 2002

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Rectal Neoplasms
Fever
Heating
Equipment and Supplies
Therapeutics
Recurrence
Combination Drug Therapy
Rectum
Sodium Chloride
Radiotherapy
Radiation
Carcinoma
Drug Therapy
Pain
Control Groups
Incidence
Neoplasms

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

Ohno, S., Sumiyoshi, Y., Mori, M., & Sugimachi, K. (2002). Hyperthermia for rectal cancer. Surgery, 131(1), S121-S127. https://doi.org/10.1067/msy.2002.119363

Hyperthermia for rectal cancer. / Ohno, Shinji; Sumiyoshi, Yasushi; Mori, Masaki; Sugimachi, Keizo.

In: Surgery, Vol. 131, No. 1, 01.2002, p. S121-S127.

Research output: Contribution to journalArticle

Ohno, S, Sumiyoshi, Y, Mori, M & Sugimachi, K 2002, 'Hyperthermia for rectal cancer', Surgery, vol. 131, no. 1, pp. S121-S127. https://doi.org/10.1067/msy.2002.119363
Ohno S, Sumiyoshi Y, Mori M, Sugimachi K. Hyperthermia for rectal cancer. Surgery. 2002 Jan;131(1):S121-S127. https://doi.org/10.1067/msy.2002.119363
Ohno, Shinji ; Sumiyoshi, Yasushi ; Mori, Masaki ; Sugimachi, Keizo. / Hyperthermia for rectal cancer. In: Surgery. 2002 ; Vol. 131, No. 1. pp. S121-S127.
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