Hypertrophic cranial pachymeningitis associated with mixed connective tissue disease; a comparison with idiopathic and infectious pachymeningitis

Mika Fujimoto, Jun ichi Kira, Hiroyuki Murai, Takeo Yoshimura, Katsumi Takizawa, Ikuo Goto

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

This is the first report describing hypertrophic cranial pachymeningitis which developed in association with mixed connective tissue disease (MCTD). A 56-year-old man with a two-year history of MCTD gradually developed symptoms of headache and blurred vision. Bilateral papilledema and increased opening pressure and mild pleocytosis of the cerebrospinal fluid were noted. Magnetic resonance imaging of the brain revealed a diffuse thickening and a gadoliniumenhancement of the cranial dura mater. While five previous patients, diagnosed as idiopathic or infectious hypertrophic cranial pachymeningitis in our department, had either otitis media or sinusitis and showed multiple cranial nerve involvement, the present patient had neither otitis media nor sinusitis and did not show any cranial nerve involvement other than papilledema.

Original languageEnglish
Pages (from-to)510-512
Number of pages3
JournalInternal Medicine
Volume32
Issue number6
DOIs
Publication statusPublished - Jan 1 1993

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Mixed Connective Tissue Disease
Papilledema
Cranial Nerves
Sinusitis
Otitis Media
Meningitis
Dura Mater
Leukocytosis
Headache
Cerebrospinal Fluid
Magnetic Resonance Imaging
Pressure
Brain

All Science Journal Classification (ASJC) codes

  • Internal Medicine

Cite this

Hypertrophic cranial pachymeningitis associated with mixed connective tissue disease; a comparison with idiopathic and infectious pachymeningitis. / Fujimoto, Mika; Kira, Jun ichi; Murai, Hiroyuki; Yoshimura, Takeo; Takizawa, Katsumi; Goto, Ikuo.

In: Internal Medicine, Vol. 32, No. 6, 01.01.1993, p. 510-512.

Research output: Contribution to journalArticle

Fujimoto, Mika ; Kira, Jun ichi ; Murai, Hiroyuki ; Yoshimura, Takeo ; Takizawa, Katsumi ; Goto, Ikuo. / Hypertrophic cranial pachymeningitis associated with mixed connective tissue disease; a comparison with idiopathic and infectious pachymeningitis. In: Internal Medicine. 1993 ; Vol. 32, No. 6. pp. 510-512.
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