Hypertrophic pachymeningitis as a result of a retropharyngeal inflammatory pseudotumor: Case report

Kenichi Matsumoto, Yoshihiro Natori, Eiko Hirokawa, Toru Iwaki, Bernard George, Griffith R. Harsh IV, Jack P. Rock, Andrew H. Kaye

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12 Citations (Scopus)

Abstract

OBJECTIVE AND IMPORTANCE: An extremely rare case of a patient with hypertrophic pachymeningitis that resulted from an inflammatory pseudotumor of retropharynx is described. CLINICAL PRESENTATION: A 59-year-old man with a 9-year history of retropharyngeal inflammatory pseudotumor sought care for severe headache and multiple cranial nerve palsies. Magnetic resonance imaging and computed tomographic scans revealed pachymeningeal enhancement and obstructive hydrocephalus attributable to marked dural thickening around the foramen magnum. INTERVENTION: Decompression of the foramen magnum, C1 laminectomy, and meningeal biopsy were performed. The histological examination of the biopsy specimen revealed chronic inflammatory infiltrate in the hypertrophic dura mater. Corticosteroid pulse therapy was subsequently completed. Clinical and neuroradiological findings improved remarkably. CONCLUSION: A new case of hypertrophic pachymeningitis as a result of a retropharyngeal inflammatory pseudotumor is presented. We review and discuss the clinical features and the pathogenic mechanisms of hypertrophic pachymeningitis.

Original languageEnglish
Pages (from-to)1061-1065
Number of pages5
JournalNeurosurgery
Volume51
Issue number4
DOIs
Publication statusPublished - Oct 1 2002

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

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    Matsumoto, K., Natori, Y., Hirokawa, E., Iwaki, T., George, B., Harsh IV, G. R., Rock, J. P., & Kaye, A. H. (2002). Hypertrophic pachymeningitis as a result of a retropharyngeal inflammatory pseudotumor: Case report. Neurosurgery, 51(4), 1061-1065. https://doi.org/10.1097/00006123-200210000-00037