Hypothalamic regulation of sodium-potassium pump activity in skeletal muscle

Hironobu Yoshimatsu, Yutaka Oomura, Toshihiko Katafuchi, Norio Akaike

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The suppression of active Na+-K+ transport in rat skeletal muscle during hypokalemia was counteracted by bilateral electrolytic lesion of the ventromedial hypothalamic nucleus. This reversal effect was unaffected even after pancreatectomy or adrenalectomy. The anomalous electrolyte content in hypokalemic rat muscles was aggravated by lesion of the dorsomedial hypothalamic nucleus and of the anterior hypothalamus. The results indicate that the hypothalamus is involve in the regulation of the Na+-K+ transport system in skeletal muscle during hypokalemia.

Original languageEnglish
Pages (from-to)17-22
Number of pages6
JournalBrain Research
Volume384
Issue number1
DOIs
Publication statusPublished - Oct 1 1986

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Sodium-Potassium-Exchanging ATPase
Hypokalemia
Skeletal Muscle
Dorsomedial Hypothalamic Nucleus
Anterior Hypothalamic Nucleus
Ventromedial Hypothalamic Nucleus
Pancreatectomy
Adrenalectomy
Electrolytes
Hypothalamus
Muscles

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

Cite this

Hypothalamic regulation of sodium-potassium pump activity in skeletal muscle. / Yoshimatsu, Hironobu; Oomura, Yutaka; Katafuchi, Toshihiko; Akaike, Norio.

In: Brain Research, Vol. 384, No. 1, 01.10.1986, p. 17-22.

Research output: Contribution to journalArticle

Yoshimatsu, H, Oomura, Y, Katafuchi, T & Akaike, N 1986, 'Hypothalamic regulation of sodium-potassium pump activity in skeletal muscle', Brain Research, vol. 384, no. 1, pp. 17-22. https://doi.org/10.1016/0006-8993(86)91214-X
Yoshimatsu, Hironobu ; Oomura, Yutaka ; Katafuchi, Toshihiko ; Akaike, Norio. / Hypothalamic regulation of sodium-potassium pump activity in skeletal muscle. In: Brain Research. 1986 ; Vol. 384, No. 1. pp. 17-22.
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